Person

Osborne, Nick

Person ID: ZDB-PERS-010221-4
Email: nicholas_osborne@med.unc.edu
URL
Affiliation
Address: Department of Biochemistry and Biophysics University of California, San Francisco Box 0448 513 Parnassus Avenue San Francisco, CA 94158 USA
Country
Phone: (415) 502-5680
Fax: (415) 476-3892
ORCID ID

Biography and Research Interest

My research focuses on the formation of the primitive heart tube. Specifically, I am interested in factors controlling the migration of the precardiac mesoderm from bilateral positions to the embryonic midline. I am using two mutations, miles apart and two of hearts, to study this process. miles apart encodes the zebrafish orthologue of the mammalian G protein-coupled receptor S1P2 and seems to function with the, as of yet unidentified, two of hearts locus to regulate precardiac mesoderm migration.

Publications

Non-Zebrafish Publications

Pogliano J, Osborne N, Sharp MD, Abanes-De Mello A, Perez A, Sun YL, Pogliano K. A vital stain for studying membrane dynamics in bacteria: a novel mechanism controlling septation during Bacillus subtilis sporulation. Mol Microbiol. 1999 Feb;31(4):1149-59.