ZFIN Person: Traver, David

ZFIN ID: ZDB-PERS-010126-6

ZFIN ID: ZDB-PERS-010126-6

Traver, David

Email:	dtraver@ucsd.edu
URL:	http://www.biology.ucsd.edu/labs/traver/index.html
Affiliation:	Traver Lab
Address:	Assistant Professor Section of Cell and Developmental Biology University of California, San Diego 9500 Gilman Drive Natural Sciences Building 6107 La Jolla, CA 92093-0380 USA
Country:	United States
Phone:	(858) 822-4593
Fax:	(858) 534-5457
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Kraus, J.M., Giovannone, D., Rydzik, R., Balsbaugh, J.L., Moss, I.L., Schwedler, J.L., Bertrand, J.Y., Traver, D., Hankenson, K.D., Crump, J.G., Youngstrom, D.W. (2022) Notch signaling enhances bone regeneration in the zebrafish mandible. Development (Cambridge, England). 149(5)

Campbell, C.A., Fursova, O., Cheng, X., Snella, E., McCune, A., Li, L., Solchenberger, B., Schmid, B., Sahoo, D., Morton, M., Traver, D., Espín-Palazón, R. (2021) A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation. Blood advances. 5:796-811

Oltova, J., Svoboda, O., Machonova, O., Svatonova, P., Traver, D., Kolar, M., Bartunek, P. (2020) Zebrafish Kit ligands cooperate with erythropoietin to promote erythroid cell expansion. Blood advances. 4:5915-5924

Espanola, S.G., Song, H., Ryu, E., Saxena, A., Kim, E.S., Manegold, J.E., Nasamran, C.A., Sahoo, D., Oh, C.K., Bickers, C., Shin, U., Grainger, S., Park, Y.H., Pandolfo, L., Kang, M.S., Kang, S., Myung, K., Cooper, K.L., Yelon, D., Traver, D., Lee, Y. (2020) Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nature cell biology. 22(12):1411-1422

Kobayashi, I., Kondo, M., Yamamori, S., Kobayashi-Sun, J., Taniguchi, M., Kanemaru, K., Katakura, F., Traver, D. (2019) Enrichment of hematopoietic stem/progenitor cells in the zebrafish kidney. Scientific Reports. 9:14205

Hong, S., Sahai-Hernandez, P., Chapla, D.G., Moremen, K.W., Traver, D., Wu, P. (2019) Direct Visualization of Live Zebrafish Glycan via Single-step Metabolic Labeling with Fluorophore-tagged Nucleotide Sugars. Angewandte Chemie (International ed. in English). 58(40):14327-14333

Grainger, S., Nguyen, N., Richter, J., Setayesh, J., Lonquich, B., Oon, C.H., Wozniak, J.M., Barahona, R., Kamei, C.N., Houston, J., Carrillo-Terrazas, M., Drummond, I.A., Gonzalez, D., Willert, K., Traver, D. (2019) EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Nature cell biology. 21(6):721-730

Gu, Q., Yang, X., Lv, J., Zhang, J., Xia, B., Kim, J.D., Wang, R., Xiong, F., Meng, S., Clements, T.P., Tandon, B., Wagner, D.S., Diaz, M.F., Wenzel, P.L., Miller, Y.I., Traver, D., Cooke, J.P., Li, W., Zon, L.I., Chen, K., Bai, Y., Fang, L. (2019) AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate. Science (New York, N.Y.). 363:1085-1088

Weijts, B., Gutierrez, E., Saikin, S.K., Ablooglu, A.J., Traver, D., Groisman, A., Tkachenko, E. (2018) Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. Nature communications. 9:5314

Bickers, C., Española, S.D., Grainger, S., Pouget, C., Traver, D. (2018) Zebrafish snai2 mutants fail to phenocopy morphant phenotypes. PLoS One. 13:e0202747

Ferrero, G., Mahony, C.B., Dupuis, E., Yvernogeau, L., Di Ruggiero, E., Miserocchi, M., Caron, M., Robin, C., Traver, D., Bertrand, J.Y., Wittamer, V. (2018) Embryonic Microglia Derive from Primitive Macrophages and Are Replaced by cmyb-Dependent Definitive Microglia in Zebrafish. Cell Reports. 24:130-141

Richter, J., Stanley, E.G., Ng, E.S., Elefanty, A.G., Traver, D., Willert, K. (2018) WNT9A Is a Conserved Regulator of Hematopoietic Stem and Progenitor Cell Development. Genes. 9(2)

van der Vaart, M., Svoboda, O., Weijts, B.G., Espín-Palazón, R., Sapp, V., Pietri, T., Bagnat, M., Muotri, A.R., Traver, D. (2017) Mecp2 regulates tnfa during zebrafish embryonic development and acute inflammation.. Disease models & mechanisms. 10(12):1439-1451

Weijts, B., Tkachenko, E., Traver, D., Groisman, A. (2017) A Four-Well Dish for High-Resolution Longitudinal Imaging of the Tail and Posterior Trunk of Larval Zebrafish. Zebrafish. 14(5):489-491

Richter, J., Traver, D., Willert, K. (2017) The role of Wnt signaling in hematopoietic stem cell development. Critical reviews in biochemistry and molecular biology. 52:414-424

Grainger, S., Lonquich, B., Oon, C.H., Nguyen, N., Willert, K., Traver, D. (2017) CRISPR Guide RNA Validation In Vitro. Zebrafish. 14(4):383-386

Keightley, M.C., Carradice, D.P., Layton, J.E., Pase, L., Bertrand, J.Y., Wittig, J.G., Dakic, A., Badrock, A.P., Cole, N.J., Traver, D., Nutt, S.L., McCoey, J., Buckle, A.M., Heath, J.K., Lieschke, G.J. (2017) The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger. Nature communications. 8:14911

Wolf, A., Aggio, J., Campbell, C., Wright, F., Marquez, G., Traver, D., Stachura, D.L. (2017) Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. Scientific Reports. 7:44644

Lardelli, R.M., Schaffer, A.E., Eggens, V.R., Zaki, M.S., Grainger, S., Sathe, S., Van Nostrand, E.L., Schlachetzki, Z., Rosti, B., Akizu, N., Scott, E., Silhavy, J.L., Heckman, L.D., Rosti, R.O., Dikoglu, E., Gregor, A., Guemez-Gamboa, A., Musaev, D., Mande, R., Widjaja, A., Shaw, T.L., Markmiller, S., Marin-Valencia, I., Davies, J.H., de Meirleir, L., Kayserili, H., Altunoglu, U., Freckmann, M.L., Warwick, L., Chitayat, D., Blaser, S., Çağlayan, A.O., Bilguvar, K., Per, H., Fagerberg, C., Christesen, H.T., Kibaek, M., Aldinger, K.A., Manchester, D., Matsumoto, N., Muramatsu, K., Saitsu, H., Shiina, M., Ogata, K., Foulds, N., Dobyns, W.B., Chi, N.C., Traver, D., Spaccini, L., Bova, S.M., Gabriel, S.B., Gunel, M., Valente, E.M., Nassogne, M.C., Bennett, E.J., Yeo, G.W., Baas, F., Lykke-Andersen, J., Gleeson, J.G. (2017) Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nature Genetics. 49(3):457-464

Boyle, G., Richter, K., Priest, H.D., Traver, D., Mockler, T.C., Chang, J.T., Kay, S.A., Breton, G. (2017) Comparative Analysis of Vertebrate Diurnal/Circadian Transcriptomes. PLoS One. 12:e0169923

Henninger, J., Santoso, B., Hans, S., Durand, E., Moore, J., Mosimann, C., Brand, M., Traver, D., Zon, L. (2017) Clonal fate mapping quantifies the number of haematopoietic stem cells that arise during development. Nature cell biology. 19(1):17-27

Li, R.A., Traver, D., Matthes, T., Bertrand, J.Y. (2016) Ndrg1b and fam49ab modulate the PTEN pathway to control T cell lymphopoiesis in the zebrafish. Blood. 128(26):3052-3060

Grainger, S., Richter, J., Palazón, R.E., Pouget, C., Lonquich, B., Wirth, S., Grassme, K.S., Herzog, W., Swift, M.R., Weinstein, B.M., Traver, D., Willert, K. (2016) Wnt9a Is Required for the Aortic Amplification of Nascent Hematopoietic Stem Cells. Cell Reports. 17:1595-1606

Kim, J.H., Shinde, D.N., Reijnders, M.R., Hauser, N.S., Belmonte, R.L., Wilson, G.R., Bosch, D.G., Bubulya, P.A., Shashi, V., Petrovski, S., Stone, J.K., Park, E.Y., Veltman, J.A., Sinnema, M., Stumpel, C.T., Draaisma, J.M., Nicolai, J., Yntema, H.G., Lindstrom, K., de Vries, B.B., Jewett, T., Santoro, S.L., Vogt, J., Bachman, K.K., Seeley, A.H., Krokosky, A., Turner, C., Rohena, L., Hempel, M., Kortüm, F., Lessel, D., Neu, A., Strom, T.M., Wieczorek, D., Bramswig, N., Laccone, F.A., Behunova, J., Rehder, H., Gordon, C.T., Rio, M., Romana, S., Tang, S., El-Khechen, D., Cho, M.T., McWalter, K., Douglas, G., Baskin, B., Begtrup, A., Funari, T., Schoch, K., Stegmann, A.P., Stevens, S.J., Zhang, D.E., Traver, D., Yao, X., MacArthur, D.G., Brunner, H.G., Mancini, G.M., Myers, R.M., Owen, L.B., Lim, S.T., Stachura, D.L., Vissers, L.E., Ahn, E.E. (2016) De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome. American journal of human genetics. 99(3):711-9

Svoboda, O., Stachura, D.L., Machonova, O., Zon, L.I., Traver, D., Bartunek, P. (2016) Ex vivo tools for the clonal analysis of zebrafish hematopoiesis. Nature Protocols. 11:1007-1020

Stachura, D.L., Traver, D. (2016) Cellular dissection of zebrafish hematopoiesis. Methods in cell biology. 133:11-53

Sertori, R., Liongue, C., Basheer, F., Lewis, K.L., Rasighaemi, P., de Coninck, D., Traver, D., Ward, A.C. (2016) Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish. Journal of immunology (Baltimore, Md. : 1950). 196(1):135-43

Campbell, C., Su, T., Lau, R.P., Shah, A., Laurie, P.C., Avalos, B., Aggio, J., Harris, E., Traver, D., Stachura, D.L. (2015) Zebrafish Embryonic Stromal Trunk (ZEST) cells support hematopoietic stem and progenitor cell (HSPC) proliferation, survival, and differentiation. Experimental hematology. 43(12):1047-61

Kim, B.J., Hancock, B.M., Bermudez, A., Cid, N.D., Reyes, E., van Sorge, N.M., Lauth, X., Smurthwaite, C.A., Hilton, B.J., Stotland, A., Banerjee, A., Buchanan, J., Wolkowicz, R., Traver, D., Doran, K.S. (2015) Bacterial induction of Snail1 contributes to blood-brain barrier disruption. The Journal of Clinical Investigation. 125(6):2473-83

Butko, E., Distel, M., Pouget, C., Weijts, B., Kobayashi, I., Ng, K., Mosimann, C., Poulain, F.E., McPherson, A., Ni, C.W., Stachura, D.L., Del Cid, N., Espín-Palazón, R., Lawson, N.D., Dorsky, R., Clements, W.K., Traver, D. (2015) Gata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo. Development (Cambridge, England). 142:1050-61

Sahai-Hernandez, P., Traver, D. (2015) Intimacy of the niche: perivascular remodeling cuddles incoming HSCs. Cell Stem Cell. 16:109-10

Kim, B.J., Hancock, B.M., Del Cid, N., Bermudez, A., Traver, D., Doran, K.S. (2015) Streptococcus agalactiae infection in zebrafish larvae. Microbial pathogenesis. 79C:57-60

Pouget, C., Peterkin, T., Simões, F.C., Lee, Y., Traver, D., Patient, R. (2014) FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway. Nature communications. 5:5588

Lee, Y., Manegold, J.E., Kim, A.D., Pouget, C., Stachura, D.L., Clements, W.K., Traver, D. (2014) FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling. Nature communications. 5:5583

Espín-Palazón, R., Stachura, D.L., Campbell, C.A., García-Moreno, D., Del Cid, N., Kim, A.D., Candel, S., Meseguer, J., Mulero, V., Traver, D. (2014) Proinflammatory signaling regulates hematopoietic stem cell emergence. Cell. 159:1070-85

Kim, A.D., Melick, C.H., Clements, W.K., Stachura, D.L., Distel, M., Panáková, D., MacRae, C., Mork, L.A., Crump, J.G., Traver, D. (2014) Discrete Notch signaling requirements in the specification of hematopoietic stem cells. The EMBO journal. 33(20):2363-73

Charbord, P., Pouget, C., Binder, H., Dumont, F., Stik, G., Levy, P., Allain, F., Marchal, C., Richter, J., Uzan, B., Pflumio, F., Letourneur, F., Wirth, H., Dzierzak, E., Traver, D., Jaffredo, T., Durand, C. (2014) A Systems Biology Approach for Defining the Molecular Framework of the Hematopoietic Stem Cell Niche. Cell Stem Cell. 15(3):376-91

Lewis, K.L., Del Cid, N., Traver, D. (2014) Perspectives on antigen presenting cells in zebrafish. Developmental and comparative immunology. 46(1):63-73

Kobayashi, I., Kobayashi-Sun, J., Kim, A.D., Pouget, C., Fujita, N., Suda, T., Traver, D. (2014) Jam1a-Jam2a interactions regulate haematopoietic stem cell fate through Notch signalling. Nature. 512(7514):319-23

Svoboda, O., Stachura, D.L., Machonova, O., Pajer, P., Brynda, J., Zon, L.I., Traver, D., Bartunek, P. (2014) Dissection of vertebrate hematopoiesis using zebrafish thrombopoietin. Blood. 124(2):220-8

Stachura, D.L., Svoboda, O., Campbell, C.A., Espín-Palazón, R., Lau, R.P., Zon, L.I., Bartunek, P., and Traver, D. (2013) The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 122(24):3918-28

Page, D.M., Wittamer, V., Bertrand, J.Y., Lewis, K.L., Pratt, D.N., Delgado, N., Schale, S.E., McGue, C., Jacobsen, B.H., Doty, A., Pao, Y., Yang, H., Chi, N.C., Magor, B.G., and Traver, D. (2013) An evolutionarily conserved program of B cell development and activation in zebrafish. Blood. 122(8):e1-e11

Clements, W.K., and Traver, D. (2012) Fish pharming: zebrafish antileukemia screening. Blood. 119(24):5614-5615

Shah, R.N., Rodriguez-Nunez, I., Eason, D.D., Haire, R.N., Bertrand, J.Y., Wittamer, V., Traver, D., Nordone, S.K., Litman, G.W., and Yoder, J.A. (2012) Development and characterization of anti-nitr9 antibodies. Advances in hematology. 2012:596925

Stachura, D.L., Svoboda, O., Lau, R.P., Balla, K.M., Zon, L.I., Bartunek, P., and Traver, D. (2011) Clonal analysis of hematopoietic progenitor cells in the zebrafish. Blood. 118(5):1274-82

Wittamer, V., Bertrand, J.Y., Gutschow, P.W., and Traver, D. (2011) Characterization of the mononuclear phagocyte system in zebrafish. Blood. 117(26):7126-7135

Clements, W.K., Kim, A.D., Ong, K.G., Moore, J.C., Lawson, N.D., and Traver, D. (2011) A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature. 474(7350):220-224

Hirota, T., Lee, J.W., Lewis, W.G., Zhang, E.E., Breton, G., Liu, X., Garcia, M., Peters, E.C., Etchegaray, J.P., Traver, D., Schultz, P.G., and Kay, S.A. (2010) High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase. PLoS Biology. 8(12):e1000559

Balla, K.M., Lugo-Villarino, G., Spitsbergen, J.M., Stachura, D.L., Hu, Y., Banuelos, K., Romo-Fewell, O., Aroian, R.V., and Traver, D. (2010) Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants. Blood. 116(19):3944-3954

Feng, H., Stachura, D.L., White, R.M., Gutierrez, A., Zhang, L., Sanda, T., Jette, C.A., Testa, J.R., Neuberg, D.S., Langenau, D.M., Kutok, J.L., Zon, L.I., Traver, D., Fleming, M.D., Kanki, J.P., and Look, A.T. (2010) T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation. Cancer Cell. 18(4):353-366

Lugo-Villarino, G., Balla, K.M., Stachura, D.L., Bañuelos, K., Werneck, M.B., and Traver, D. (2010) Identification of dendritic antigen-presenting cells in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 107(36):15850-15855

Bertrand, J.Y., Cisson, J.L., Stachura, D.L., and Traver, D. (2010) Notch signaling distinguishes two waves of definitive hematopoiesis in the zebrafish embryo. Blood. 115(14):2777-2783

Bertrand, J.Y., Chi, N.C., Santoso, B., Teng, S., Stainier, D.Y., and Traver, D. (2010) Haematopoietic stem cells derive directly from aortic endothelium during development. Nature. 464(7285):108-111

Yoder, J.A., Turner, P.M., Wright, P.D., Wittamer, V., Bertrand, J.Y., Traver, D., and Litman, G.W. (2010) Developmental and tissue-specific expression of NITRs. Immunogenetics. 62(2):117-122

Amigo, J.D., Ackermann, G.E., Cope, J.J., Yu, M., Cooney, J.D., Ma, D., Langer, N.B., Shafizadeh, E., Shaw, G.C., Horsley, W., Trede, N.S., Davidson, A.J., Barut, B.A., Zhou, Y., Wojiski, S.A., Traver, D., Moran, T.B., Kourkoulis, G., Hsu, K., Kanki, J.P., Shah, D.I., Lin, H.F., Handin, R.I., Cantor, A.B., and Paw, B.H. (2009) The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 114(21):4654-4663

Stachura, D.L., Reyes, J.R., Bartunek, P., Paw, B.H., Zon, L.I., and Traver, D. (2009) Zebrafish kidney stromal cell lines support multilineage hematopoiesis. Blood. 114(2):279-289

Bertrand, J.Y., and Traver, D. (2009) Hematopoietic cell development in the zebrafish embryo. Current opinion in hematology. 16(4):243-248

Clements, W.K., Ong, K.G., and Traver, D. (2009) Zebrafish wnt3 is expressed in developing neural tissue. Developmental Dynamics : an official publication of the American Association of Anatomists. 238(7):1788-1795

Cantagrel, V., Silhavy, J.L., Bielas, S.L., Swistun, D., Marsh, S.E., Bertrand, J.Y., Audollent, S., Attié-Bitach, T., Holden, K.R., Dobyns, W.B., Traver, D., Al-Gazali, L., Ali, B.R., Lindner, T.H., Caspary, T., Otto, E.A., Hildebrandt, F., Glass, I.A., Logan, C.V., Johnson, C.A., Bennett, C., Brancati, F.; International Joubert Syndrome Related Disorders Study Group, Valente, E.M., Woods, C.G., Gleeson, J.G. (2008) Mutations in the cilia gene ARL13B lead to the classical form of Joubert syndrome. American journal of human genetics. 83(2):170-179

Bertrand, J.Y., Kim, A.D., Teng, S., and Traver, D. (2008) CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis. Development (Cambridge, England). 135(10):1853-1862

Bertrand, J.Y., Kim, A.D., Violette, E.P., Stachura, D.L., Cisson, J.L., and Traver, D. (2007) Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development (Cambridge, England). 134(23):4147-4156

Yoder, J.A., Orcutt, T.M., Traver, D., and Litman, G.W. (2007) Structural characteristics of zebrafish orthologs of adaptor molecules that associate with transmembrane immune receptors. Gene. 401(1-2):154-164

Wei, S., Zhou, J.M., Chen, X., Shah, R.N., Liu, J., Orcutt, T.M., Traver, D., Djeu, J.Y., Litman, G.W., and Yoder, J.A. (2007) The zebrafish activating immune receptor Nitr9 signals via Dap12. Immunogenetics. 59(10):813-821

Ablooglu, A.J., Kang, J., Handin, R.I., Traver, D., and Shattil, S.J. (2007) The zebrafish vitronectin receptor: Characterization of integrin alphaV and beta3 expression patterns in early vertebrate development. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(8):2268-2276

Zon, L.I., Traver, D., Davidson,A.J., Van Slyke, C. (2006) ZFIN Anatomy Working Group: Blood. Manually curated data.

Shaw, G.C., Cope, J.J., Li, L., Corson, K., Hersey, C., Ackermann, G.E., Gwynn, B., Lambert, A.J., Wingert, R.A., Traver, D., Trede, N.S., Barut, B.A., Zhou, Y., Minet, E., Donovan, A., Brownlie, A., Balzan, R., Weiss, M.J., Peters, L.L., Kaplan, J., Zon, L.I., and Paw, B.H. (2006) Mitoferrin is essential for erythroid iron assimilation. Nature. 440(7080):96-100

Panagos, P.G., Dobrinski, K.P., Chen, X., Grant, A.W., Traver, D., Djeu, J.Y., Wei, S., and Yoder, J.A. (2006) Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish. Immunogenetics. 58(1):31-40

Lin, H.F., Traver, D., Zhu, H., Dooley, K., Paw, B.H., Zon, L.I., and Handin, R.I. (2005) Analysis of thrombocyte development in CD41-GFP transgenic zebrafish. Blood. 106(12):3803-3810

Burns, C.E., Traver, D., Mayhall, E., Shepard, J.L., and Zon, L.I. (2005) Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes & Development. 19(19):2331-2342

Fraenkel, P.G., Traver, D., Donovan, A., Zahrieh, D., and Zon, L.I. (2005) Ferroportin1 is required for normal iron cycling in zebrafish. J. Clin. Invest.. 115(6):1532-1541

Zhu, H., Traver, D., Davidson, A.J., Dibiase, A., Thisse, C., Thisse, B., Nimer, S., and Zon, L.I. (2005) Regulation of the lmo2 promoter during hematopoietic and vascular development in zebrafish. Developmental Biology. 281(2):256-269

Patton, E.E., Widlund, H.R., Kutok, J.L., Kopani, K.R., Amatruda, J.F., Murphey, R.D., Berghmans, S., Mayhall, E.A., Traver, D., Fletcher, C.D., Aster, J.C., Granter, S.R., Look, A.T., Lee, C., Fisher, D.E., and Zon, L.I. (2005) BRAF Mutations Are Sufficient to Promote Nevi Formation and Cooperate with p53 in the Genesis of Melanoma. Current biology : CB. 15(3):249-254

Hsu, K., Traver, D., Kutok, J.L., Hagen, A., Liu, T.X., Paw, B.H., Rhodes, J., Berman, J., Zon, L.I., Kanki, J.P., and Look, A.T. (2004) The pu.1 promoter drives myeloid gene expression in zebrafish. Blood. 104(5):1291-1297

Traver, D., Winzeler, A., Stern, H.M., Mayhall, E.A., Langenau, D.M., Kutok, J.L., Look, A.T., and Zon, L.I. (2004) Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation. Blood. 104(5):1298-1305

Ransom, D.G., Bahary, N., Niss, K., Traver, D., Burns, C., Trede, N.S., Paffett-Lugassy, N., Saganic, W.J., Lim, C.A., Hersey, C., Zhou, Y., Barut, B.A., Lin, S., Kingsley, P.D., Palis, J., Orkin, S.H., and Zon, L.I. (2004) The Zebrafish moonshine Gene Encodes Transcriptional Intermediary Factor 1gamma, an Essential Regulator of Hematopoiesis. PLoS Biology. 2(8):E237

Langenau, D.M., Ferrando, A.A., Traver, D., Kutok, J.L., Hezel, J.P., Kanki, J.P., Zon, L.I., Look, A.T., and Trede, N.S. (2004) In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 101(19):7369-7374

Trede, N.S., Langenau, D.M., Traver, D., Look, A.T., and Zon, L.I. (2004) The use of zebrafish to understand immunity. Immunity. 20(4):367-379

Traver, D. (2004) Cellular dissection of zebrafish hematopoiesis. The Zebrafish: Cellular and Developmental Biology,2nd Ed. Methods Cell Biol.. 76:127-149

Traver, D., Paw, B.H., Poss, K.D., Penberthy, W.T., Lin, S., and Zon, L.I. (2003) Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants. Nature immunology. 4(12):1238-1246

Langenau, D.M., Traver, D., Ferrando, A.A., Kutok, J.L., Aster, J.C., Kanki, J.P., Lin, S., Prochownik, E., Trede, N.S., Zon, L.I., and Look, A.T. (2003) Myc-induced T cell leukemia in transgenic zebrafish. Science (New York, N.Y.). 299(5608):887-890

Traver, D., Herbomel, P., Patton, E.E., Murphey, R.D., Yoder, J.A., Litman, G.W., Catic, A., Amemiya, C.T., Zon, L.I., and Trede, N.S. (2003) The zebrafish as a model organism to study development of the immune system. Advances in immunology. 81:253-330

Traver, D. and Zon, L.I. (2002) Walking the walk: migration and other common themes in blood and vascular development. Cell. 108(6):731-734

NON-ZEBRAFISH PUBLICATIONS
BitMansour, A., S. M. Burns, D. Traver, K. Akashi, C. H. Contag, I. L. Weissman, and J. M. Y. Brown. 2002. Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood, In press.

NaNakorn, T.*, D. Traver*, K. Akashi, and I. L. Weissman. 2002. Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J. Clin. Invest., 109(12): 1579-1585.

Traver, D., T. Miyamoto, J. Christensen, K. Akashi, and I. L. Weissman. 2001. Fetal liver myelopoiesis occurs through distinct, prospectively isolatable progenitor subsets. Blood, 98(3): 627-635.

DiMartino, J.*, L. Selleri*, D. Traver*, M. Firpo, R. Warnke, J. Rhee, S. O'Garman, I. L. Weissman, and M. L. Cleary. 2001. The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver. Blood, 98(3): 618-626.

Manz, M. G., D. Traver, T. Miyamoto, I. L. Weissman, and K. Akashi. 2001. Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood, 97: 3333-3341.

Traver, D.*, K. Akashi*, M. Manz*, M. Merad, T. Miyamoto, E. G. Engleman, and I. L. Weissman. 2000. Development of CD8a-Positive dendritic cells from a common myeloid progenitor. Science, 290: 2152-2154.

Akashi, K.*, D. Traver*, T. Miyamoto, and I.L. Weissman. 2000. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404: 193-197.

Traver, D., K. Akashi, I.L. Weissman, and E. Lagasse. 1998. Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia. Immunity 9, no. 1:47-57.