ZFIN Person: Ho, Shiu-Ying

ZFIN ID: ZDB-PERS-010125-1

ZFIN ID: ZDB-PERS-010125-1

Ho, Shiu-Ying

Email:	sho@mail.jci.tju.edu
URL:	http://www.jefferson.edu/biochemistry/faculty_profile.cfm?key=sxh124
Affiliation:	Ho Lab
Address:	Kimmel Cancer Center Department of Microbiology and Immunonolgy Thomas Jefferson University 484 Jefferson Alumni Hall 1020 Locust Street Philadelphia, PA 19107 USA
Country:	United States
Phone:	(215) 503-2472
Fax:	(215) 923-7144
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Lipid Metabolism

PUBLICATIONS

Li, Q., Frank, M., Akiyama, M., Shimizu, H., Ho, S.Y., Thisse, C., Thisse, B., Sprecher, E., and Uitto, J. (2011) Abca12-mediated lipid transport and Snap29-dependent trafficking of lamellar granules are crucial for epidermal morphogenesis in a zebrafish model of ichthyosis. Disease models & mechanisms. 4(6):777-85

Liu, H.Y., Lee, N., Tsai, T.Y., and Ho, S.Y. (2010) Zebrafish fat-free, a novel Arf effector, regulates phospholipase D to mediate lipid and glucose metabolism. Biochimica et biophysica acta. Molecular and cell biology of lipids. 1801(12):1330-1340

Li, Q., Sadowski, S., Frank, M., Chai, C., Váradi, A., Ho, S.Y., Lou, H., Dean, M., Thisse, C., Thisse, B., and Uitto, J. (2010) The abcc6a Gene Expression Is Required for Normal Zebrafish Development. The Journal of investigative dermatology. 130(11):2561-2568

Kim, S.H., Choi, H.Y., So, J.H., Kim, C.H., Ho, S.Y., Frank, M., Li, Q., and Uitto, J. (2010) Zebrafish type XVII collagen: Gene structures, expression profiles, and morpholino "knock-down" phenotypes. Matrix biology : journal of the International Society for Matrix Biology. 29(7):629-637

Zoeller, J.J., Pimtong, W., Corby, H., Goldoni, S., Iozzo, A.E., Owens, R.T., Ho, S.Y., and Iozzo, R.V. (2009) A central role for decorin during vertebrate convergent extension. The Journal of biological chemistry. 284(17):11728-11737

Zoeller, J.J., McQuillan, A., Whitelock, J., Ho, S.Y., and Iozzo, R.V. (2008) A central function for perlecan in skeletal muscle and cardiovascular development. The Journal of cell biology. 181(2):381-394

Ouyang, M., Garnett, A.T., Han, T.M., Hama, K., Lee, A., Deng, Y., Lee, N., Liu, H.Y., Amacher, S.L., Farber, S.A., and Ho, S.Y. (2008) A web based resource characterizing the zebrafish developmental profile of over 16,000 transcripts. Gene expression patterns : GEP. 8(3):171-180

Ho, S.Y., Lorent, K., Pack, M., and Farber, S.A. (2006) Zebrafish fat-free is required for intestinal lipid absorption and Golgi apparatus structure. Cell Metabolism. 3(4):289-300

Thorpe, J.L., Doitsidou, M., Ho, S.-Y., Raz, E., and Farber, S.A. (2004) Germ Cell Migration in Zebrafish Is Dependent on HMGCoA Reductase Activity and Prenylation. Developmental Cell. 6:5-302

Ho, S.Y., Thorpe, J.L., Deng, Y., Santana, E., DeRose, R.A., and Farber, S.A. (2004) Lipid metabolism in zebrafish. The Zebrafish: Cellular and Developmental Biology,2nd Ed. Methods Cell Biol.. 76:87-108

Ho, S.Y., Pack, M., and Farber, S.A. (2003) Analysis of small molecule metabolism in zebrafish. Methods in enzymology. 364:408-426

Farber, S.A., Pack, M., Ho, S.Y., Johnson, I.D., Wagner, D.S., Dosch, R., Mullins, M.C., Hendrickson, H.S., Hendrickson, E.K., and Halpern, M.E. (2001) Genetic analysis of digestive physiology using fluorescent phospholipid reporters. Science (New York, N.Y.). 292(5520):1385-1388

Ho, S.Y., Pack, M., and Farber, S.A. (2001) Real-time imaging of lipid processing in wild type and mutant zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(5):A1102

NON-ZEBRAFISH PUBLICATIONS
Trotter, P.J., Ho, S.Y., and J. Storch (1996) Fatty acid uptake by Caco-2 human intestinal cells. J. Lipid Res. 37:336-346

Ho, S.Y., and J. Storch (2001) Common mechanisms of monoacylglycerol and fatty acid uptake by human intestinal Caco-2 cells. Am. J. Physiol. 281:C1106-C1117

Ho, S.Y., Delgado, L., and J. Storch (2002) Monoacylglycerol metabolism in human intestinal Caco-2 cells: evidence for compartmentation and hydrolysis. J. Biol. Chem. 277:1816-1823