ZFIN ID: ZDB-PERS-001220-2
Baxendale, Sarah
Email: s.baxendale@sheffield.ac.uk
URL:
Affiliation: Whitfield Lab
Address: MRC Centre Development for Developmental and Biomedical Genetics, University of Sheffield Firth Court Western Bank Sheffield, S10 2TN United Kingdom
Country: United Kingdom
Phone: 44-114-222-2803
Fax: 44-114-222-2788
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Toms, M., Dubis, A.M., de Vrieze, E., Tracey-White, D., Mitsios, A., Hayes, M., Broekman, S., Baxendale, S., Utoomprurkporn, N., Bamiou, D., Bitner-Glindzicz, M., Webster, A.R., Van Wijk, E., Moosajee, M. (2020) Clinical and preclinical therapeutic outcome metrics for USH2A-related disease. Human molecular genetics. 29(11):1882-1899
Diamantopoulou, E., Baxendale, S., de la Vega de León, A., Asad, A., Holdsworth, C.J., Abbas, L., Gillet, V.J., Wiggin, G.R., Whitfield, T.T. (2019) Identification of compounds that rescue otic and myelination defects in the zebrafish adgrg6 (gpr126) mutant. eLIFE. 8:
Hartwell, R.D., England, S.J., Monk, N.A.M., van Hateren, N.J., Baxendale, S., Marzo, M., Lewis, K.E., Whitfield, T.T. (2019) Anteroposterior patterning of the zebrafish ear through Fgf- and Hh-dependent regulation of hmx3a expression. PLoS Genetics. 15:e1008051
Kenyon, E.J., Kirkwood, N.K., Kitcher, S.R., O'Reilly, M., Derudas, M., Cantillon, D.M., Goodyear, R.J., Secker, A., Baxendale, S., Bull, J.C., Waddell, S.J., Whitfield, T.T., Ward, S.E., Kros, C.J., Richardson, G.P. (2017) Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death. JCI insight. 2(24)
Gurung, R., Ono, Y., Baxendale, S., Lee, S.L., Moore, S., Calvert, M., Ingham, P.W. (2017) The Zebrafish frozen Mutant Is a Model for Human Myopathy Associated with Mutation of the Unconventional Myosin MYO18B. Genetics. 205(2):725-735
Baxendale, S., van Eeden, F., Wilkinson, R. (2017) The Power of Zebrafish in Personalised Medicine. Advances in experimental medicine and biology. 1007:179-197
Baxendale, S., Whitfield, T.T. (2016) Methods to study the development, anatomy, and function of the zebrafish inner ear across the life course. Methods in cell biology. 134:165-209
Stooke-Vaughan, G.A., Obholzer, N.D., Baxendale, S., Megason, S.G., Whitfield, T.T. (2015) Otolith tethering in the zebrafish otic vesicle requires Otogelin and α-Tectorin. Development (Cambridge, England). 142(6):1137-45
Geng, F.S., Abbas, L., Baxendale, S., Holdsworth, C.J., Swanson, A.G., Slanchev, K., Hammerschmidt, M., Topczewski, J., and Whitfield, T.T. (2013) Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene. Development (Cambridge, England). 40(21):4362-4374
Baxendale, S., Holdsworth, C.J., Santoscoy, P.M., Harrison, M.R., Fox, J., Parkin, C.A., Ingham, P.W., and Cunliffe, V.T. (2012) Identification of compounds with novel anti-convulsant properties in a zebrafish model of epileptic seizures. Disease models & mechanisms. 5(6):773-784
Thompson, M.J., Louth, J.C., Ferrara, S., Jackson, M.P., Sorrell, F.J., Cochrane, E.J., Gever, J., Baxendale, S., Silber, B.M., Roehl, H.H., and Chen, B. (2011) Discovery of 6-substituted indole-3-glyoxylamides as lead antiprion agents with enhanced cell line activity, improved microsomal stability and low toxicity. European Journal of Medicinal Chemistry. 46(9):4125-32
Baxendale, S., Chen, C.K., Tang, H., Davison, C., Hateren, L.V., Croning, M.D., Humphray, S.J., Hubbard, S.J., and Ingham, P.W. (2009) Expression screening and annotation of a zebrafish myoblast cDNA library. Gene expression patterns : GEP. 9(2):73-82
Hammond, K.L., Baxendale, S., McCauley, D.W., Ingham, P.W., and Whitfield, T.T. (2009) Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evolution & development. 11(1):27-40
Baxendale, S., Davison, C., Muxworthy, C., Wolff, C., Ingham, P.W., and Roy, S. (2004) The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling. Nature Genetics. 36(1):88-93

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