ZFIN ID: ZDB-PERS-001207-2
Peers, Bernard
Email: bpeers@ulg.ac.be
Affiliation: Laboratory of Zebrafish Development and Disease Models
and also: Martial Lab
Address: Laboratory of Molecular Biology and Genetic Engineering Institute of Chemistry University of Liège Allée du 6 Août Bâtiment B6 Liège (Sart Tilman), B-4000 Belgium
Phone: 32-4-366-3374
Fax: 32-4-366-2968


Reuter, A.S., Stern, D., Bernard, A., Goossens, C., Lavergne, A., Flasse, L., Von Berg, V., Manfroid, I., Peers, B., Voz, M.L. (2022) Identification of an evolutionarily conserved domain in Neurod1 favouring enteroendocrine versus goblet cell fate. PLoS Genetics. 18:e1010109
Carril Pardo, C.A., Massoz, L., Dupont, M.A., Bergemann, D., Bourdouxhe, J., Lavergne, A., Tarifeño-Saldivia, E., Helker, C.S., Stainier, D.Y., Peers, B., Voz, M.M., Manfroid, I. (2022) A δ-cell subpopulation with pro-β cell identity contributes to efficient age-independent recovery in a zebrafish diabetes model. eLIFE. 11:
López-Pérez, A.R., Balwierz, P.J., Lenhard, B., Muller, F., Wardle, F.C., Manfroid, I., Voz, M.L., Peers, B. (2021) Identification of downstream effectors of retinoic acid specifying the zebrafish pancreas by integrative genomics. Scientific Reports. 11:22717
Lavergne, A., Tarifeño-Saldivia, E., Pirson, J., Reuter, A.S., Flasse, L., Manfroid, I., Voz, M.L., Peers, B. (2020) Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes. BMC Biology. 18:109
Nepal, C., Hadzhiev, Y., Balwierz, P., Tarifeño-Saldivia, E., Cardenas, R., Wragg, J.W., Suzuki, A.M., Carninci, P., Peers, B., Lenhard, B., Andersen, J.B., Müller, F. (2020) Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing. Nature communications. 11:168
Rapino, F., Delaunay, S., Rambow, F., Zhou, Z., Tharun, L., De Tullio, P., Sin, O., Shostak, K., Schmitz, S., Piepers, J., Ghesquière, B., Karim, L., Charloteaux, B., Jamart, D., Florin, A., Lambert, C., Rorive, A., Jerusalem, G., Leucci, E., Dewaele, M., Vooijs, M., Leidel, S.A., Georges, M., Voz, M., Peers, B., Büttner, R., Marine, J.C., Chariot, A., Close, P. (2018) Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 558:605-609
Bergemann, D., Massoz, L., Bourdouxhe, J., Carril Pardo, C.A., Voz, M.L., Peers, B., Manfroid, I. (2018) Nifurpirinol : a more potent and reliable substrate compared to metronidazole for nitroreductase-mediated cell ablations. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 26(2):238-244
Facchinello, N., Tarifeño-Saldivia, E., Grisan, E., Schiavone, M., Peron, M., Mongera, A., Ek, O., Schmitner, N., Meyer, D., Peers, B., Tiso, N., Argenton, F. (2017) Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration. Scientific Reports. 7:9605
Tarifeño-Saldivia, E., Lavergne, A., Bernard, A., Padamata, K., Bergemann, D., Voz, M.L., Manfroid, I., Peers, B. (2017) Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes. BMC Biology. 15:21
Verstraelen, S., Peers, B., Maho, W., Hollanders, K., Remy, S., Berckmans, P., Covaci, A., Witters, H. (2016) Phenotypic and biomarker evaluation of zebrafish larvae as an alternative model to predict mammalian hepatotoxicity. Journal of applied toxicology : JAT. 36(9):1194-206
Halluin, C., Madelaine, R., Naye, F., Peers, B., Roussigné, M., Blader, P. (2016) Habenular Neurogenesis in Zebrafish Is Regulated by a Hedgehog, Pax6 Proneural Gene Cascade. PLoS One. 11:e0158210
Janssen, L., Dupont, L., Bekhouche, M., Noel, A., Leduc, C., Voz, M., Peers, B., Cataldo, D., Apte, S.S., Dubail, J., Colige, A. (2016) ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis. Angiogenesis. 19(1):53-65
Ishibashi, M., Manning, E., Shoubridge, C., Krecsmarik, M., Hawkins, T.A., Giacomotto, J., Zhao, T., Mueller, T., Bader, P.I., Cheung, S.W., Stankiewicz, P., Bain, N.L., Hackett, A., Reddy, C.C., Mechaly, A.S., Peers, B., Wilson, S.W., Lenhard, B., Bally-Cuif, L., Gecz, J., Becker, T.S., Rinkwitz, S. (2015) Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene. Human genetics. 134(11-12):1163-82
Ghaye, A.P., Bergemann, D., Tarifeño-Saldivia, E., Flasse, L.C., Von Berg, V., Peers, B., Voz, M.L., Manfroid, I. (2015) Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biology. 13:70
Flasse, L.C., Pirson, J.L., Stern, D.G., Von Berg, V., Manfroid, I., Peers, B., and Voz, M.L. (2013) Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biology. 11(1):78
Flasse, L., Stern, D.G., Pirson, J.L., Manfroid, I., Peers, B., and Voz, M.L. (2013) The bHLH transcription factor Ascl1a is essential for the specification of the intestinal secretory cells and mediates Notch signaling in the zebrafish intestine. Developmental Biology. 376(2):187-197
Djiotsa, J., Verbruggen, V., Giacomotto, J., Ishibashi, M., Manning, E., Rinkwitz, S., Manfroid, I., Lvoz, M., and Peers, B. (2012) Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression. BMC Developmental Biology. 12(1):37
Manfroid, I., Ghaye, A., Naye, F., Detry, N., Palm, S., Pan, L., Ma, T.P., Huang, W., Rovira, M., Martial, J.A., Parsons, M.J., Moens, C.B., Voz, M.L., and Peers, B. (2012) Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration. Developmental Biology. 366(2):268-278
Arkhipova, V., Wendik, B., Devos, N., Ek, O., Peers, B., and Meyer, D. (2012) Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish. Developmental Biology. 365(1):290-302
Lambaerts, K., Van Dyck, S., Mortier, E., Ivarssonm, Y., Degeest, G., Luyten, A., Vermeiren, E., Peers, B., David, G., and Zimmermann, P. (2012) Syntenin, a syndecan adaptor and an Arf6 phosphatidylinositol 4,5-bisphosphate effector, is essential for epiboly and gastrulation cell movements in zebrafish. Journal of Cell Science. 125(5):1129-1140
Naye, F., Voz, M.L., Detry, N., Hammerschmidt, M., Peers, B., and Manfroid, I. (2012) Essential roles of zebrafish bmp2a, fgf10 and fgf24 in the specification of the ventral pancreas. Molecular biology of the cell. 23(5):945-954
Voz, M.L., Coppieters, W., Manfroid, I., Baudhuin, A., Von Berg, V., Charlier, C., Meyer, D., Driever, W., Martial, J.A., and Peers, B. (2012) Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing. PLoS One. 7(4):e34671
Laudadio, I., Manfroid, I., Achouri, Y., Schmidt, D., Wilson, M.D., Cordi, S., Thorrez, L., Knoops, L., Jacquemin, P., Schuit, F., Pierreux, C.E., Odom, D.T., Peers, B., and Lemaigre, F.P. (2012) A Feedback Loop Between The Liver-Enriched Transcription Factor Network and Mir-122 Controls Hepatocyte Differentiation. Gastroenterology. 142(1):119-29
Verbruggen, V., Ek, O., Georlette, D., Delporte, F., Von Berg, V., Detry, N., Biemar, F., Coutinho, P., Martial, J.A., Voz, M.L., Manfroid, I., and Peers, B. (2010) The Pax6b homeodomain is dispensable for pancreatic endocrine cell differentiation in zebrafish. The Journal of biological chemistry. 285(18):13863-13873
Binot, A.C., Manfroid, I., Flasse, L., Winandy, M., Motte, P., Martial, J.A., Peers, B., and Voz, M.L. (2010) Nkx6.1 and nkx6.2 regulate alpha- and beta-cell formation in zebrafish by acting on pancreatic endocrine progenitor cells. Developmental Biology. 340(2):397-407
Soyer, J., Flasse, L., Raffelsberger, W., Beucher, A., Orvain, C., Peers, B., Ravassard, P., Vermot, J., Voz, M.L., Mellitzer, G., and Gradwohl, G. (2010) Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development (Cambridge, England). 137(2):203-212
Delporte, F.M., Pasque, V., Devos, N., Manfroid, I., Voz, M.L., Motte, P., Biemar, F., Martial, J.A., and Peers, B. (2008) Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors. BMC Developmental Biology. 8:53
Pendeville, H., Winandy, M., Manfroid, I., Nivelles, O., Motte, P., Pasque, V., Peers, B., Struman, I., Martial, J.A., and Voz, M.L. (2008) Zebrafish Sox7 and Sox18 function together to control arterial-venous identity. Developmental Biology. 317(2):405-416
Manfroid, I., Delporte, F., Baudhuin, A., Motte, P., Neumann, C.J., Voz, M.L., Martial, J.A., and Peers, B. (2007) Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development. Development (Cambridge, England). 134(22):4011-4021
Stetsyuk, V., Peers, B., Mavropoulos, A., Verbruggen, V., Thisse, B., Thisse, C., Motte, P., Duvillie, B., and Scharfmann, R. (2007) Calsenilin is required for endocrine pancreas development in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 236(6):1517-1525
Peeters, H., Voz, M.L., Verschueren, K., De Cat, B., Pendeville, H., Thienpont, B., Schellens, A., Belmont, J.W., David, G., Van De Ven, W.J., Fryns, J.P., Gewillig, M., Huylebroeck, D., Peers, B., and Devriendt, K. (2006) Sesn1 is a Novel Gene for Left-Right Asymmetry and Mediating Nodal Signaling. Human molecular genetics. 15(22):3369-3377
Pendeville, H., Peers, B., Kas, K., and Voz, M.L. (2006) Cloning and embryonic expression of zebrafish PLAG genes. Gene expression patterns : GEP. 6(3):267-276
Mavropoulos, A., Devos, N., Biemar, F., Zecchin, E., Argenton, F., Edlund, H., Motte, P., Martial, J.A., and Peers, B. (2005) sox4b is a key player of pancreatic alpha cell differentiation in zebrafish. Developmental Biology. 285(1):211-223
de Cat, B., Muyldermans, S.Y., Coomans, C., Degeest, G., Vanderschueren, B., Creemers, J., Biemar, F., Peers, B., and David, G. (2003) Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements. The Journal of cell biology. 163(3):625-635
Biemar, F., Baraldi, F., Devos, N., Holzschuh, J., Martial, J.A., Driever, W., and Peers, B. (2002) Analysis of meis genes expression in zebrafish suggests a role in the development of organs derived from the endoderm. Developmental Biology. 247(2):495
Devos, N., Deflorian, G., Biemar, F., Bortolussi, M., Martial, J.A., Peers, B., and Argenton, F. (2002) Differential expression of two somatostatin genes during zebrafish embryonic development. Mechanisms of Development. 115(1-2):133-137
Biemar, F., Devos, N., Martial, J.A., Driever, W., and Peers, B. (2001) Cloning and expression of the TALE superclass homeobox Meis2 gene during zebrafish embryonic development. Mechanisms of Development. 109(2):427-431
Biemar, F., Argenton, F., Schmidtke, R., Epperlein, S., Peers, B., and Driever, W. (2001) Pancreas development in zebrafish: early dispersed appearance of endocrine hormone expressing cells and their convergence to form the definitive islet. Developmental Biology. 230(2):189-203