ZFIN ID: ZDB-PERS-001103-3
Ryu, Soojin
Email: Soojin.Ryu@mpimf-heidelberg.mpg.de
Affiliation: Ryu Lab
and also: Ryu Lab Heidelberg
Address: Max Planck Institute for Medical Research Developmental Genetics of Nervous System Jahnstrasse 29 Heidelberg, 69120 Germany
Country: Germany
Phone: +49 6221 486 210


Cook, A., Beckmann, H., Azap, R., Ryu, S. (2023) Acute stress modulates social approach and social maintenance in adult zebrafish. eNeuro. 10(9):
Herget, U., Ryu, S., De Marco, R.J. (2023) Altered glucocorticoid reactivity and behavioral phenotype in rx3-/- larval zebrafish. Frontiers in endocrinology. 14:11873271187327
Gemmer, A., Mirkes, K., Anneser, L., Eilers, T., Kibat, C., Mathuru, A., Ryu, S., Schuman, E. (2022) Oxytocin receptors influence the development and maintenance of social behavior in zebrafish (Danio rerio). Scientific Reports. 12:4322
Anneser, L., Gemmer, A., Eilers, T., Alcantara, I.C., Loos, A.Y., Ryu, S., Schuman, E.M. (2022) The neuropeptide Pth2 modulates social behavior and anxiety in zebrafish. iScience. 25:103868
Anneser, L., Alcantara, I.C., Gemmer, A., Mirkes, K., Ryu, S., Schuman, E.M. (2020) The neuropeptide Pth2 dynamically senses others via mechanosensation. Nature. 588(7839):653-657
Castillo-Ramírez, L.A., Ryu, S., De Marco, R.J. (2019) Active behaviour during early development shapes glucocorticoid reactivity. Scientific Reports. 9:12796
Langebeck-Jensen, K., Shahar, O.D., Schuman, E.M., Langer, J.D., Ryu, S. (2019) Larval Zebrafish Proteome Regulation in Response to an Environmental Challenge. Proteomics. 19(14):e1900028
Nagpal, J., Herget, U., Choi, M.K., Ryu, S. (2018) Anatomy, development, and plasticity of the neurosecretory hypothalamus in zebrafish. Cell and tissue research. 375(1):5-22
Ryu, S., De Marco, R.J. (2017) Performance on innate behaviour during early development as a function of stress level. Scientific Reports. 7:7840
Biechl, D., Tietje, K., Ryu, S., Grothe, B., Gerlach, G., Wullimann, M.F. (2017) Identification of accessory olfactory system and medial amygdala in the zebrafish. Scientific Reports. 7:44295
Herget, U., Gutierrez-Triana, J.A., Salazar Thula, O., Knerr, B., Ryu, S. (2017) Single-Cell Reconstruction of Oxytocinergic Neurons Reveals Separate Hypophysiotropic and Encephalotropic Subtypes in Larval Zebrafish. eNeuro. 4(1)
Beretta, C.A., Dross, N., Guglielmi, L., Bankhead, P., Soulika, M., Gutierrez-Triana, J.A., Paolini, A., Poggi, L., Falk, J., Ryu, S., Kapsimali, M., Engel, U., Carl, M. (2017) Early Commissural Diencephalic Neurons Control Habenular Axon Extension and Targeting. Current biology : CB. 27(2):270–278
De Marco, R.J., Thiemann, T., Groneberg, A.H., Herget, U., Ryu, S. (2016) Optogenetically enhanced pituitary corticotroph cell activity post-stress onset causes rapid organizing effects on behaviour. Nature communications. 7:12620
Vom Berg-Maurer, C.M., Trivedi, C.A., Bollmann, J.H., De Marco, R.J., Ryu, S. (2016) The Severity of Acute Stress Is Represented by Increased Synchronous Activity and Recruitment of Hypothalamic CRH Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 36:3350-62
Arturo Gutierrez-Triana, J., Herget, U., Castillo-Ramirez, L.A., Lutz, M., Yeh, C.M., De Marco, R.J., Ryu, S. (2015) Manipulation of interrenal cell function in developing zebrafish using genetically targeted ablation and an optogenetic tool. Endocrinology. 156(9):3394-401
Groneberg, A.H., Herget, U., Ryu, S., De Marco, R.J. (2015) Positive taxis and sustained responsiveness to water motions in larval zebrafish. Frontiers in neural circuits. 9:9
Herget, U., Ryu, S. (2015) Coexpression analysis of nine neuropeptides in the neurosecretory preoptic area of larval zebrafish. Frontiers in Neuroanatomy. 9:2
Gutierrez-Triana, J., Herget, U., Lichtner, P., Castillo-Ramírez, L.A., Ryu, S. (2014) A vertebrate-conserved cis -regulatory module for targeted expression in the main hypothalamic regulatory region for the stress response. BMC Developmental Biology. 14:41
Preuss, S.J., Trivedi, C.A., Vom Berg-Maurer, C.M., Ryu, S., Bollmann, J.H. (2014) Classification of Object Size in Retinotectal Microcircuits. Current biology : CB. 24(20):2376-85
De Marco, R.J., Groneberg, A.H., Yeh, C.M., Treviño, M., Ryu, S. (2014) The behavior of larval zebrafish reveals stressor-mediated anorexia during early vertebrate development. Frontiers in behavioral neuroscience. 8:367
Gasser, C., Taiber, S., Yeh, C.M., Wittig, C.H., Hegemann, P., Ryu, S., Wunder, F., Möglich, A. (2014) Engineering of a red-light-activated human cAMP/cGMP-specific phosphodiesterase. Proceedings of the National Academy of Sciences of the United States of America. 111(24):8803-8
Herget, U., Wolf, A., Wullimann, M.F., and Ryu, S. (2014) Molecular neuroanatomy and chemoarchitecture of the neurosecretory preoptic-hypothalamic area in zebrafish larvae. The Journal of comparative neurology. 522(7):1542-64
Yeh, C.M., Glöck, M., and Ryu, S. (2013) An optimized whole-body cortisol quantification method for assessing stress levels in larval zebrafish. PLoS One. 8(11):e79406
De Marco, R.J., Groneberg, A.H., Yeh, C.M., Castillo Ramírez, L.A., and Ryu, S. (2013) Optogenetic elevation of endogenous glucocorticoid level in larval zebrafish. Frontiers in neural circuits. 7:82
Wolf, A., and Ryu, S. (2013) Specification of posterior hypothalamic neurons requires coordinated activities of Fezf2, Otp, Sim1a and Foxb1.2. Development (Cambridge, England). 140(8):1762-1773
Gabriel, J.P., Trivedi, C.A., Maurer, C.M., Ryu, S., and Bollmann, J.H. (2012) Layer-specific targeting of direction-selective neurons in the zebrafish optic tectum. Neuron. 76(6):1147-1160
Beretta, C.A., Dross, N., Guiterrez-Triana, J.A., Ryu, S., and Carl, M. (2012) Habenula circuit development: past, present, and future. Frontiers in Neurogenesis. 6:51
Tay, T.L., Ronneberger, O., Ryu, S., Nitschke, R., and Driever, W. (2011) Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nature communications. 2:171
Kastenhuber, E., Kratochwil, C.F., Ryu, S., Schweitzer, J., and Driever, W. (2010) Genetic dissection of dopaminergic and noradrenergic contributions to catecholaminergic tracts in early larval zebrafish. The Journal of comparative neurology. 518(4):439-458
Löhr, H., Ryu, S., and Driever, W. (2009) Zebrafish diencephalic A11-related dopaminergic neurons share a conserved transcriptional network with neuroendocrine cell lineages. Development (Cambridge, England). 136(6):1007-1017
Meng, S., Ryu, S., Zhao, B., Zhang, D.Q., Driever, W., and McMahon, D.G. (2008) Targeting retinal dopaminergic neurons in tyrosine hydroxylase-driven green fluorescent protein transgenic zebrafish. Molecular Vision. 14:2475-2483
Filippi, A., Duerr, K., Ryu, S., Willaredt, M., Holzschuh, J., and Driever, W. (2007) Expression and function of nr4a2, lmx1b, and pitx3 in zebrafish dopaminergic and noradrenergic neuronal development. BMC Developmental Biology. 7(1):135
Brockschmidt, A., Todt, U., Ryu, S., Hoischen, A., Landwehr, C., Birnbaum, S., Frenck, W., Radlwimmer, B., Lichter, P., Engels, H., Driever, W., Kubisch, C.,and Weber, R.G. (2007) Severe mental retardation with breathing abnormalities (Pitt-Hopkins syndrome) is caused by haploinsufficiency of the neuronal bHLH transcription factor TCF4. Human molecular genetics. 16(12):1488-1494
Ryu, S., Mahler, J., Acampora, D., Holzschuh, J., Erhardt, S., Omodei, D., Simeone, A., and Driever, W. (2007) Orthopedia Homeodomain Protein Is Essential for Diencephalic Dopaminergic Neuron Development. Current biology : CB. 17(10):873-880
Chapouton, P., Adolf, B., Leucht, C., Tannhauser, B., Ryu, S., Driever, W., Bally-Cuif, L. (2006) her5 expression reveals a pool of neural stem cells in the adult zebrafish midbrain. Development (Cambridge, England). 133(21):4293-4303
Durr, K., Holzschuh, J., Filippi, A., Ettl, A.K., Ryu, S., Shepherd, I.T., and Driever, W. (2006) Differential Roles of Transcriptional Mediator Complex Subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 During Zebrafish Retinal Development. Genetics. 174(2):693-705
Ryu, S., and Driever, W. (2006) Minichromosome maintenance proteins as markers for proliferation zones during embryogenesis. Cell cycle (Georgetown, Tex.). 5(11):1140-1142
Ryu, S., Holzschuh, J., Mahler, J., and Driever, W. (2006) Genetic analysis of dopaminergic system development in zebrafish. Journal of neural transmission. Supplementum. 70:61-66
Ryu, S., Holzschuh, J., Erhardt, S., Ettl, A.K., and Driever, W. (2005) Depletion of minichromosome maintenance protein 5 in the zebrafish retina causes cell-cycle defect and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 102(51):18467-18472
Holzschuh, J., Ryu, S., Aberger, F., and Driever, W. (2001) Dopamine transporter expression distinguishes dopaminergic neurons from other catecholaminergic neurons in the developing zebrafish embryo. Mechanisms of Development. 101(1-2):237-243

Ryu, S., Zhou, S., Laudrner, A.G., and Tjian, R. (1999). Transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1. Nature.

Ryu, S. and Tjian, R. (1999). Purification of the transcription cofactor complex CRSP.
Proc. Natl. Acad. Sci. USA. 96: 7137-7142

Näär, A.M., Ryu, S., and Tjian, R. (1999). Co-factor requirements for transcriptional activation by Sp1. Introductory Chapter. Cold Spring Harbor Symposia on Quantitative Biology: Mechanisms of Transcription. 63:189-199. Review.