ZFIN Person: Jurynec, Michael

ZFIN ID: ZDB-PERS-000802-1

ZFIN ID: ZDB-PERS-000802-1

Jurynec, Michael

Email:	mjurynec@genetics.utah.edu
URL:
Affiliation:	Grunwald Lab
Address:	Eccles Institute of Human Genetics Department of Human Genetics University of Utah Medical School 15 North 2030 East, Room 5250 Salt Lake City, UT 84112 USA
Country:	United States
Phone:	(801) 581-4442
Fax:	(801) 581-5374
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

EDUCATION:

Emory University, Atlanta, Georgia, USA, Bachelor of Science in Biology, May 1999.

University Of Utah, Salt Lake City, Utah, USA, Ph.D. Candidate, Program in Neuroscience.

PUBLICATIONS

Styrkarsdottir, U., Stefansdottir, L., Thorleifsson, G., Stefansson, O.A., Saevarsdottir, S., Lund, S.H., Rafnar, T., Hoshijima, K., Novak, K., Oreiro, N., Rego-Perez, I., Hansen, C., Kazmers, N., Kiemeney, L.A., Blanco, F.J., Barker, T., Kloppenburg, M., Jurynec, M.J., Gudbjartsson, D.F., Jonsson, H., Thorsteinsdottir, U., Stefansson, K. (2023) Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect. Annals of the rheumatic diseases. 82(6):873-880

Teerlink, C.C., Jurynec, M.J., Hernandez, R., Stevens, J., Hughes, D.C., Brunker, C.P., Rowe, K., Grunwald, D.J., Facelli, J.C., Cannon-Albright, L.A. (2020) A role for the MEGF6 gene in predisposition to osteoporosis. Annals of human genetics. 85(2):58-72

Santoriello, C., Sporrij, A., Yang, S., Flynn, R.A., Henriques, T., Dorjsuren, B., Custo Greig, E., McCall, W., Stanhope, M.E., Fazio, M., Superdock, M., Lichtig, A., Adatto, I., Abraham, B.J., Kalocsay, M., Jurynec, M., Zhou, Y., Adelman, K., Calo, E., Zon, L.I. (2020) RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells. Nature cell biology. 22(4):372-379

Jurynec, M.J., Bai, X., Bisgrove, B.W., Jackson, H., Nechiporuk, A., Palu, R.A.S., Grunwald, H.A., Su, Y.C., Hoshijima, K., Yost, H.J., Zon, L.I., Grunwald, D.J. (2019) The Paf1 Complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors. Development (Cambridge, England). 146(24):

Hoshijima, K., Jurynec, M.J., Klatt Shaw, D., Jacobi, A.M., Behlke, M.A., Grunwald, D.J. (2019) Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish. Developmental Cell. 51(5):645-657.e4

Jurynec, M.J., Sawitzke, A.D., Beals, T.C., Redd, M.J., Stevens, J., Otterud, B., Leppert, M.F., Grunwald, D.J. (2018) Corrigenda: A hyperactivating proinflammatory RIPK2 allele associated with early-onset osteoarthritis. Human molecular genetics. 27:2406

Klatt Shaw, D., Gunther, D., Jurynec, M.J., Chagovetz, A.A., Ritchie, E., Grunwald, D.J. (2018) Intracellular Calcium Mobilization Is Required for Sonic Hedgehog Signaling. Developmental Cell. 45(4):512-525.e5

Jurynec, M.J., Sawitzke, A.D., Beals, T.C., Redd, M.J., Stevens, J., Otterud, B., Leppert, M.H., Grunwald, D.J. (2018) A hyperactivating proinflammatory RIPK2 allele associated with early-onset osteoarthritis. Human molecular genetics. 27(13):2383-2391

Hoshijima, K., Jurynec, M.J., Grunwald, D.J. (2016) Precise genome editing by homologous recombination. Methods in cell biology. 135:121-47

Dahlem, T.J., Hoshijima, K., Jurynec, M.J., Gunther, D., Starker, C.G., Locke, A.S., Weis, A.M., Voytas, D.F., and Grunwald, D.J. (2012) Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome. PLoS Genetics. 8(8):e1002861

Wythe, J.D., Jurynec, M.J., Urness, L.D., Jones, C.A., Sabeh, M.K., Werdich, A.A., Sato, M., Yost, H.J., Grunwald, D.J., MacRae, C.A., and Li, D.Y. (2011) Hadp1, a newly identified pleckstrin homology domain protein, is required for cardiac contractility in zebrafish. Disease models & mechanisms. 4(5):607-21

Jurynec, M.J., and Grunwald, D.J. (2010) SHIP2, a factor associated with diet-induced obesity and insulin sensitivity, attenuates FGF signaling in vivo. Disease models & mechanisms. 3(11-12):733-742

Bai, X., Kim, J., Yang, Z., Jurynec, M.J., Akie, T.E., Lee, J., LeBlanc, J., Sessa, A., Jiang, H., DiBiase, A., Zhou, Y., Grunwald, D.J., Lin, S., Cantor, A.B., Orkin, S.H., and Zon, L.I. (2010) TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 142(1):133-143

Jurynec, M.J., Xia, R., Mackrill, J.J., Gunther, D., Crawford, T., Flanigan, K.M., Abramson, J.J., Howard, M.T., and Grunwald, D.J. (2008) Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle. Proceedings of the National Academy of Sciences of the United States of America. 105(34):12485-12490

Jurynec, M.J. (2006) Mechanisms of zebrafish development and disease. Ph.D. Thesis. :162p

Lamason, R.L., Mohideen, M.A., Mest, J.R., Wong, A.C., Norton, H.L., Aros, M.C., Jurynec, M.J., Mao, X., Humphreville, V.R., Humbert, J.E., Sinha, S., Moore, J.L., Jagadeeswaran, P., Zhao, W., Ning, G., Makalowska, I., McKeigue, P.M., O'donnell, D., Kittles, R., Parra, E.J., Mangini, N.J., Grunwald, D.J., Shriver, M.D., Canfield, V.A., and Cheng, K.C. (2005) SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science (New York, N.Y.). 310(5755):1782-1786

Hutson, L.D., Jurynec, M.J., Yeo, S.Y., Okamoto, H., and Chien, C.B. (2003) Two divergent slit1 genes in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 228(3):358-369

NON-ZEBRAFISH PUBLICATIONS