Morpholino

MO4-rab5c

ID

ZDB-MRPHLNO-201020-1

Name

MO4-rab5c

Previous Names

None

Target

rab5c (1)

Sequence

5' - CATGCCAACAGGCTGGACAACAGGA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO4-rab5c

Expressed Gene	Anatomy	Figures
efnb2a	vasculature	Fig 4 from Heng et al., 2020
gata1a	erythroid progenitor cell	Fig 2 from Heng et al., 2020
gata2b	dorsal aorta	Fig 4 from Heng et al., 2020
gfi1aa	endothelial cell	Fig 2 from Heng et al., 2020
myb	hematopoietic multipotent progenitor cell hematopoietic stem cell	Fig 2 from Heng et al., 2020
runx1	hematopoietic multipotent progenitor cell hematopoietic stem cell	Fig 2 , Fig 4 from Heng et al., 2020

Phenotype

Phenotype resulting from MO4-rab5c

Phenotype	Fish	Figures
caudal hematopoietic tissue hematopoietic cell EGFP expression decreased distribution, abnormal	la2Tg/+ + MO4-rab5c	Fig 2 from Heng et al., 2020
dorsal aorta gata2b expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 4 from Heng et al., 2020
endothelial cell mCherry expression decreased distribution, abnormal	jh11Tg/+; y1Tg/+ + MO4-rab5c	Fig 4 from Heng et al., 2020
endothelial cell gfi1aa expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 2 from Heng et al., 2020
erythroid progenitor cell gata1a expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 2 from Heng et al., 2020
hematopoietic multipotent progenitor cell runx1 expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 2 , Fig 4 from Heng et al., 2020
hematopoietic multipotent progenitor cell myb expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 2 from Heng et al., 2020
hematopoietic stem cell runx1 expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 2 , Fig 4 from Heng et al., 2020
hematopoietic stem cell myb expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 2 from Heng et al., 2020
vasculature efnb2a expression decreased distribution, abnormal	WT + MO4-rab5c	Fig 4 from Heng et al., 2020

Phenotype of all Fish created by or utilizing MO4-rab5c

Phenotype	Fish	Conditions	Figures
hematopoietic multipotent progenitor cell runx1 expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 2 , Fig 4 from Heng et al., 2020
dorsal aorta gata2b expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 4 from Heng et al., 2020
hematopoietic stem cell runx1 expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 2 , Fig 4 from Heng et al., 2020
erythroid progenitor cell gata1a expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 2 from Heng et al., 2020
hematopoietic multipotent progenitor cell myb expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 2 from Heng et al., 2020
hematopoietic stem cell myb expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 2 from Heng et al., 2020
endothelial cell gfi1aa expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 2 from Heng et al., 2020
vasculature efnb2a expression decreased distribution, abnormal	WT + MO4-rab5c	standard conditions	Fig 4 from Heng et al., 2020
caudal hematopoietic tissue hematopoietic cell EGFP expression decreased distribution, abnormal	la2Tg/+ + MO4-rab5c	standard conditions	Fig 2 from Heng et al., 2020
endothelial cell mCherry expression decreased distribution, abnormal	jh11Tg/+; y1Tg/+ + MO4-rab5c	standard conditions	Fig 4 from Heng et al., 2020
dorsal aorta hematopoietic cell EGFP expression decreased distribution, abnormal	s896Tg/+; zf169Tg/+ + MO4-rab5c	standard conditions	Fig 2 from Heng et al., 2020
ventral aorta hematopoietic cell EGFP expression decreased distribution, abnormal	s896Tg/+; zf169Tg/+ + MO4-rab5c	standard conditions	Fig 2 from Heng et al., 2020

Citations