Morpholino

MO1-cgasa

ID

ZDB-MRPHLNO-171109-2

Name

MO1-cgasa

Previous Names

MO1-cgas
MO1-mb21d1
zpcGAS (1)

Target

cgasa (1)

Sequence

5' - CTGGTCTCCTGTGGCTGCTCATGAT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Translation-blocking MO.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-cgasa

No data available

Phenotype

Phenotype resulting from MO1-cgasa

Phenotype	Fish	Figures
caudal fin curled, abnormal	WT + MO1-cgasa	Fig. 6 from Ge et al., 2015
hindbrain atrophied, abnormal	WT + MO1-cgasa	Fig. 6 from Ge et al., 2015
whole organism decreased pigmentation, abnormal	WT + MO1-cgasa	Fig. 6 from Ge et al., 2015

Phenotype of all Fish created by or utilizing MO1-cgasa

Phenotype	Fish	Conditions	Figures
whole organism isg15 expression increased amount, abnormal	WT + MO1-cgasa	viral treatment by injection: Human alphaherpesvirus 1	Fig. 6 from Ge et al., 2015
whole organism rsad2 expression increased amount, abnormal	WT + MO1-cgasa	viral treatment by injection: Human alphaherpesvirus 1	Fig. 6 from Ge et al., 2015
whole organism decreased pigmentation, abnormal	WT + MO1-cgasa	standard conditions	Fig. 6 from Ge et al., 2015
hindbrain atrophied, abnormal	WT + MO1-cgasa	standard conditions	Fig. 6 from Ge et al., 2015
whole organism ifnphi1 expression increased amount, abnormal	WT + MO1-cgasa	viral treatment by injection: Human alphaherpesvirus 1	Fig. 6 from Ge et al., 2015
caudal fin curled, abnormal	WT + MO1-cgasa	standard conditions	Fig. 6 from Ge et al., 2015
hematopoietic multipotent progenitor cell Ab1-tbk1 labeling amount, ameliorated	ddx41^{sa14887/sa14887} + MO1-cgasa	standard conditions	Fig. 4 from Weinreb et al., 2021
cGAS/STING signaling pathway increased process quality, ameliorated	ddx41^{sa14887/sa14887} + MO1-cgasa	standard conditions	Fig. 4 from Weinreb et al., 2021
hematopoietic multipotent progenitor cell GFP expression amount, ameliorated	ddx41^{sa14887/sa14887}; la2Tg/la2Tg + MO1-cgasa	standard conditions	Fig. 5 from Weinreb et al., 2021
hematopoietic stem cell proliferation normal frequency, ameliorated	ddx41^{sa14887/sa14887}; la2Tg/la2Tg + MO1-cgasa	standard conditions	Fig. 5 from Weinreb et al., 2021
hematopoietic multipotent progenitor cell canonical NF-kappaB signal transduction increased magnitude, ameliorated	ddx41^{sa14887/sa14887}; nc1Tg/nc1Tg + MO1-cgasa	standard conditions	Fig. 4 from Weinreb et al., 2021
hematopoietic multipotent progenitor cell EGFP expression amount, ameliorated	ddx41^{sa14887/sa14887}; nc1Tg/nc1Tg + MO1-cgasa	standard conditions	Fig. 4 from Weinreb et al., 2021

Citations