Morpholino

MO1-cxcl8b.1

ID

ZDB-MRPHLNO-140630-2

Name

MO1-cxcl8b.1

Previous Names

MO cxcl8-l2 E1/I1 (1)

Target

cxcl8b.1 (1)

Sequence

5' - GCCAATGAGGGTAAGCAGATACTAA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-cxcl8b.1

No data available

Phenotype

Phenotype resulting from MO1-cxcl8b.1

Phenotype	Fish	Figures
intersegmental vessel morphology, abnormal	i114Tg; y1Tg + MO1-cxcl8b.1	Fig. S1 from Zuñiga-Traslaviña et al., 2017

Phenotype of all Fish created by or utilizing MO1-cxcl8b.1

Phenotype	Fish	Conditions	Figures
caudal fin Ab1-cxcl8b.1 labeling decreased amount, abnormal	WT + MO1-cxcl8b.1	amputation: caudal fin	Fig. S2 from de Oliveira et al., 2015
whole organism decreased life span, exacerbated	WT + MO1-cxcl8b.1	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 1 from de Oliveira et al., 2015
neutrophil chemotaxis decreased occurrence, abnormal	WT + MO1-cxcl8b.1	amputation: caudal fin	Fig. 1 from de Oliveira et al., 2015
neutrophil chemotaxis decreased occurrence, abnormal	i114Tg + MO1-cxcl8b.1	amputation: caudal fin	Fig. 1, Fig. 3 from de Oliveira et al., 2015
leukocyte migration involved in inflammatory response process quality, abnormal	i114Tg + MO1-cxcl8b.1	physical alteration: caudal fin	Fig. 2, Fig. 4, Fig. 5, Fig. 6 from de Oliveira et al., 2013
defense response to bacterium decreased occurrence, abnormal	i114Tg + MO1-cxcl8b.1	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 2 from de Oliveira et al., 2015
neutrophil chemotaxis decreased occurrence, abnormal	i114Tg + MO1-cxcl8b.1	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 2 from de Oliveira et al., 2015
neutrophil-mediated killing of bacterium decreased occurrence, abnormal	i114Tg + MO1-cxcl8b.1	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 2 from de Oliveira et al., 2015
intersegmental vessel morphology, abnormal	i114Tg; y1Tg + MO1-cxcl8b.1	standard conditions	Fig. S1 from Zuñiga-Traslaviña et al., 2017
caudal fin neutrophil decreased amount, abnormal	i114Tg; y1Tg + MO1-cxcl8b.1	transection: caudal fin musculature	Fig. 2 from Zuñiga-Traslaviña et al., 2017
blood neutrophil decreased amount, abnormal	i114Tg; y1Tg + MO1-cxcl8b.1	transection: caudal fin musculature	Fig. 2 from Zuñiga-Traslaviña et al., 2017
neutrophil chemotaxis disrupted, abnormal	i114Tg; y1Tg + MO1-cxcl8b.1	transection: caudal fin musculature	Fig. 2 from Zuñiga-Traslaviña et al., 2017
receptor internalization increased occurrence, abnormal	cu101Tg + MO1-cxcl8b.1	transection: ventral fin fold	Fig. 2 from Coombs et al., 2019
neutrophil chemotaxis decreased occurrence, abnormal	i114Tg + MO1-cxcl8b.1 + MO1-lyn	amputation: caudal fin	Fig. 3 from de Oliveira et al., 2015

Citations