Morpholino

MO1-musk

ID

ZDB-MRPHLNO-050218-2

Name

MO1-musk

Previous Names

None

Target

Sequence

5' - TATTGTCTTACCTCCATTCTACGGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Blocks the splice donor site of musk SV1 (splice variant 1) exon 2.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-musk

Expressed Gene	Anatomy	Figures
chrna1	myotome plasma membrane	Fig. 1 from Jing et al., 2009

Phenotype

Phenotype resulting from MO1-musk

Phenotype	Fish	Figures
receptor clustering disrupted, abnormal	WT + MO1-musk	Fig. 1 from Lefebvre et al., 2007
skeletal muscle acetylcholine-gated channel clustering arrested, abnormal	WT + MO1-musk	Fig. 1 from Jing et al., 2009
synaptic assembly at neuromuscular junction disrupted, abnormal	WT + MO1-musk	Fig. 1 from Lefebvre et al., 2007

Phenotype of all Fish created by or utilizing MO1-musk

Phenotype	Fish	Conditions	Figures
receptor clustering disrupted, abnormal	WT + MO1-musk	standard conditions	Fig. 1 from Lefebvre et al., 2007
synaptic assembly at neuromuscular junction disrupted, abnormal	WT + MO1-musk	standard conditions	Fig. 1 from Lefebvre et al., 2007
skeletal muscle acetylcholine-gated channel clustering arrested, abnormal	WT + MO1-musk	standard conditions	Fig. 1 from Jing et al., 2009

Citations