miRNA Gene
mir133b
- ID
- ZDB-MIRNAG-090929-141
- Name
- microRNA 133b
- Symbol
- mir133b Nomenclature History
- Previous Names
- Type
- miRNA_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Acts upstream of or within miRNA-mediated gene silencing by mRNA destabilization and neuron projection regeneration. Is expressed in several structures, including central nervous system; heart; muscle; otic vesicle; and pectoral fin.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| MO1-mir133 | N/A | Mishima et al., 2009 |
| MO2-mir133 | N/A | Mishima et al., 2009 |
| MO3-mir133b | N/A | (2) |
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Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mir133b-201
(1)
|
Ensembl | 84 nt | ||
| miRNA | mir133b-001 (1) | 22 nt | |||
| miRNA | mir133b*-002 (1) | 22 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
- Davide, B., Marcello, C., Carol, L., Veronica, V., Roberta, B., Davide, C., Claudio, S., Gornati, R., Nicla, R. (2022) Can Blebbistatin block the hypertrophy status in the zebrafish exvivo cardiac model?. Biochimica et biophysica acta. Molecular basis of disease. 1868(10):166471
- Desvignes, T., Bardou, P., Montfort, J., Sydes, J., Guyomar, C., George, S., Postlethwait, J.H., Bobe, J. (2022) FishmiRNA: An evolutionarily supported microRNA annotation and expression database for ray-finned fishes. Molecular Biology and Evolution. 39(2)
- Huang, Y., Jiang, B., Xia, Y., Wang, J., Ji, C., Tong, J., Chen, T., Jiang, Y. (2020) Downregulation of miR-133a contributes to the cardiac developmental toxicity of trichloroethylene in zebrafish. Chemosphere. 251:126610
- Romano, N., Ceci, M. (2020) Are microRNAs responsible for cardiac hypertrophy in fish and mammals? What we can learn in the activation process in a zebrafish ex vivo model. Biochimica et biophysica acta. Molecular basis of disease. 1866(11):165896
- Duran, B.O.D.S., Dal-Pai-Silva, M., Garcia de la Serrana, D. (2019) Rainbow trout slow myoblast cell culture as a model to study slow skeletal muscle and the characterization of mir-133 and mir-499 families as a case study. The Journal of experimental biology. 223(Pt 2):
- Zhang, Q.L., Dong, Z.X., Luo, Z.W., Jiao, Y.J., Guo, J., Deng, X.Y., Wang, F., Chen, J.Y., Lin, L.B. (2019) MicroRNA profile of immune response in gills of zebrafish (Danio rerio) upon Staphylococcus aureus infection. Fish & shellfish immunology. 87:307-314
- Ceci, M., Carlantoni, C., Missinato, M.A., Bonvissuto, D., Di Giacomo, B., Contu, R., Romano, N. (2018) Micro RNAs are involved in activation of epicardium during zebrafish heart regeneration. Cell death discovery. 4:41
- Klett, H., Jürgensen, L., Most, P., Busch, M., Günther, F., Dobreva, G., Leuschner, F., Hassel, D., Busch, H., Boerries, M. (2018) Delineating the Dynamic Transcriptome Response of mRNA and microRNA during Zebrafish Heart Regeneration. Biomolecules. 9(1)
- Huang, R., Chen, M., Yang, L., Wagle, M., Guo, S., Hu, B. (2017) MicroRNA-133b Negatively Regulates Zebrafish Single Mauthner-Cell Axon Regeneration through Targeting tppp3 in Vivo.. Frontiers in molecular neuroscience. 10:375
- Schoen, C., Aschrafi, A., Thonissen, M., Poelmans, G., Von den Hoff, J.W., Carels, C.E.L. (2017) MicroRNAs in Palatogenesis and Cleft Palate. Frontiers in Physiology. 8:165
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