ZFIN Lab: Physiology and Cell Dynamics

ZFIN ID: ZDB-LAB-231019-2

Physiology and Cell Dynamics

PI/Director:	Llopis, Juan Francisco
Co-PI / Senior Researcher:	Domingo Moreno, Beatriz Nava Hernandez, Eduardo Salgado Almario, Jussep Vicente Ruiz, Manuel
Contact Person:	Llopis, Juan Francisco
Email:	Juan.Llopis@uclm.es
URL:
Address:	Facultad de Medicina de Albacete. Department of Medical Sciences. Physiology Lab. Av. Almansa, 14 02002 Albacete Spain
Country:	Spain
Phone:	+34967599315
Fax:
Line Designation:	ucl

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 6 genomic features

STATEMENT OF RESEARCH INTERESTS

Zebrafish as model for cardiovascular physiology and pathophysiology studies.
Fluorescent and bioluminescent biosensors for in vivo imaging.

LAB MEMBERS

Martínez Sielva, Antonio Graduate Student

García Blázquez, Aarón Research Staff

Cifuentes Verdú, Carmen Technical Staff

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Salgado-Almario, J., Molina, Y., Vicente, M., Martínez-Sielva, A., Rodríguez-García, R., Vincent, P., Domingo, B., Llopis, J. (2023) ERG potassium channels and T-type calcium channels contribute to the pacemaker and atrioventricular conduction in zebrafish larvae. Acta physiologica (Oxford, England). 240(2):e14075

Vicente, M., Salgado-Almario, J., Valiente-Gabioud, A.A., Collins, M.M., Vincent, P., Domingo, B., Llopis, J. (2022) Early calcium and cardiac contraction defects in a model of phospholamban R9C mutation in zebrafish. Journal of Molecular and Cellular Cardiology. 173:127-140

Salgado-Almario, J., Vicente, M., Molina, Y., Martinez-Sielva, A., Vincent, P., Domingo, B., Llopis, J. (2022) Simultaneous imaging of calcium and contraction in the beating heart of zebrafish larvae. Theranostics. 12:1012-1029

Vicente, M., Salgado-Almario, J., Martínez-Sielva, A., Llopis, J., Domingo, B. (2022) Optimized Aequorin Reconstitution Protocol to Visualize Calcium Ion Transients in the Heart of Transgenic Zebrafish Embryos In Vivo. Methods in molecular biology (Clifton, N.J.). 2524:271-280

Vicente, M., Salgado-Almario, J., Collins, M.M., Martínez-Sielva, A., Minoshima, M., Kikuchi, K., Domingo, B., Llopis, J. (2021) Cardioluminescence in Transgenic Zebrafish Larvae: A Calcium Imaging Tool to Study Drug Effects and Pathological Modeling. Biomedicines. 9(10):

Salgado-Almario, J., Vicente, M., Vincent, P., Domingo, B., Llopis, J. (2020) Mapping Calcium Dynamics in the Heart of Zebrafish Embryos with Ratiometric Genetically Encoded Calcium Indicators. International Journal of Molecular Sciences. 21(18):

Vicente, M., Salgado-Almario, J., Soriano, J., Burgos, M., Domingo, B., Llopis, J. (2019) Visualization of Mitochondrial Ca²⁺ Signals in Skeletal Muscle of Zebrafish Embryos with Bioluminescent Indicators. International Journal of Molecular Sciences. 20(21):

Bakayan, A., Domingo, B., Miyawaki, A., Llopis, J. (2015) Imaging Ca(2+) activity in mammalian cells and zebrafish with a novel red-emitting aequorin variant. Pflugers Archiv : European journal of physiology. 467(9):2031-42