ZFIN ID: ZDB-LAB-220914-1
Callewaert Lab
PI/Director: Callewaert, Bert
Co-PI / Senior
Researcher:
Sips, Patrick
Contact Person: Callewaert, Bert
Email: Bert.Callewaert@Ugent.be
URL:
Address:
Country: Belgium
Phone: +32-9-332 24 77
Fax: +32-9-332 49 70
Line Designation: cmg


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 2 genomic features


STATEMENT OF RESEARCH INTERESTS
The Callewaert Lab focuses on the clinical and molecular delineation of Mendelian connective tissue disorders, intellectual disability syndromes, and congenital cardiopathies. His team pursues to elucidate the underlying pathophysiology of diverse monogenic conditions using cellular systems and animal models (zebrafish and mice models).
Bert Callewaert (MD, 2004, PhD 2010) is pediatrician and clinical geneticist. He is appointed associate professor in human genetics at Ghent University and Head of Clinic at the Center for Medical Genetics of the Ghent University Hospital. He is a Senior Clinical Investigator of the Research Foundation – Flanders. He is active in societal outreach through national (BeSHG) and international (Cutis laxa internationale, A Twist of Fate-ATS, Myhre professional advisory board) organizations and active in organization of patient care (ERN-Skin, ITHACA, VNZZ-huid).


LAB MEMBERS
Beyens, Aude Graduate Student del Rocio Pérez Baca, Maria Graduate Student Guerreiro Santana Ramos Da Silva, Marta Graduate Student
Hamerlinck, Lisa Graduate Student Verlee, Maxim Graduate Student De Saffel, Hanna Research Staff
Tapaneeyaphan, Piyanoot Research Staff Vanhooydonck, Michiel


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Van Impe, M., Caboor, L., Deleeuw, V., De Rycke, K., Vanhooydonck, M., De Backer, J., Segers, P., Sips, P. (2023) Application of an automated analysis framework for pulsed wave Doppler cardiac ultrasound measurements to generate reference data in adult zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 325(6):R782-R796
Pottie, L., Van Gool, W., Vanhooydonck, M., Hanisch, F.G., Goeminne, G., Rajkovic, A., Coucke, P., Sips, P., Callewaert, B. (2021) Loss of zebrafish atp6v1e1b, encoding a subunit of vacuolar ATPase, recapitulates human ARCL type 2C syndrome and identifies multiple pathobiological signatures. PLoS Genetics. 17:e1009603
Pottie, L., Adamo, C.S., Beyens, A., Lütke, S., Tapaneeyaphan, P., De Clercq, A., Salmon, P.L., De Rycke, R., Gezdirici, A., Gulec, E.Y., Khan, N., Urquhart, J.E., Newman, W.G., Metcalfe, K., Efthymiou, S., Maroofian, R., Anwar, N., Maqbool, S., Rahman, F., Altweijri, I., Alsaleh, M., Abdullah, S.M., Al-Owain, M., Hashem, M., Houlden, H., Alkuraya, F.S., Sips, P., Sengle, G., Callewaert, B. (2021) Bi-allelic premature truncating variants in LTBP1 cause cutis laxa syndrome. American journal of human genetics. 108(6):1095-1114