ZFIN ID: ZDB-LAB-201119-2
Kathy Qian Luo Lab
PI/Director: Luo, Kathy Qian
Contact Person: Jia, Hao
Email: kluo@um.edu.mo
URL: http://fhs.um.edu.mo/en/staff/kathy-luo/
Address: 4038, N22, University of Macau, Taipa, Macao SAR
Country: China
Phone: +853-88224233
Fax:
Line Designation: umo


GENOMIC FEATURES ORIGINATING FROM THIS LAB
Show all 2 genomic features


STATEMENT OF RESEARCH INTERESTS
Our research interests include: (1) Identify driver genes that can increase cancer cells survival in circulation, metastasis and tumor growth using zebrafish and mice as model animals. (2) Discover new agents against metastatic and drug resistant cancer cells. (3) Generate transgenic zebrafish for aging research and toxicity study.


LAB MEMBERS
Jia, Hao Post-Doc Yang, Hongmai Post-Doc Chen, Tiantian Graduate Student
Hao, Meng Graduate Student Huang, Bin Graduate Student Li, Koukou Graduate Student
Li, Tianhong Graduate Student Peng, Zheng Graduate Student Tong, Haibo Graduate Student
Wu, Renfei Graduate Student Yuan, Mingheng Graduate Student Zhang, Xiaoying Graduate Student
Zhou, Muya Graduate Student


ZEBRAFISH PUBLICATIONS OF LAB MEMBERS
Yan, Y., Xing, F., Cao, J., Hu, Y., Li, L., Gao, Z., Jia, H., Miao, K., Shao, F., Deng, C.X., Luo, K.Q., Lee, L.T.O., Liu, T.M. (2022) Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer. Redox Biology. 59:102578102578
Tao, J., Wei, Z., Cheng, Y., Xu, M., Li, Q., Lee, S.M., Ge, W., Luo, K.Q., Wang, X., Zheng, Y. (2022) Apoptosis-Sensing Xenograft Zebrafish Tumor Model for Anticancer Evaluation of Redox-Responsive Cross-Linked Pluronic Micelles. ACS applied materials & interfaces. 14(35):39775-39786
Yang, H., Jia, H., Zhao, Q., Luo, K.Q. (2022) Visualization of natural killer cell-mediated killing of cancer cells at single-cell resolution in live zebrafish. Biosensors & bioelectronics. 216:114616
Jia, H., Luo, K.Q. (2020) Fluorescence resonance energy transfer-based sensor zebrafish for detecting toxic agents with single-cell sensitivity. Journal of hazardous materials. 408:124826
Jia, H., Song, Y., Huang, B., Ge, W., Luo, K.Q. (2020) Engineered Sensor Zebrafish for Fast Detection and Real-Time Tracking of Apoptosis at Single-Cell Resolution in Live Animals. ACS sensors. 5(3):823-830
Wang, Q., Luo, M., Wei, N., Chang, A., Luo, K.Q. (2019) Development of a Liposomal Formulation of Acetyltanshinone IIA for Breast Cancer Therapy. Molecular pharmaceutics. 16(9):3873-3886
Ma, S., Fu, A., Chiew, G.G., Luo, K.Q. (2017) Hemodynamic shear stress stimulates migration and extravasation of tumor cells by elevating cellular oxidative level. Cancer letters. 388:239-248
Wang, Q., Wei, N., Liu, X., Chang, A., Qian Luo, K. (2017) Enhancement of the bioavailability of a novel anticancer compound (acetyltanshinone IIA) by encapsulation within mPEG-PLGA nanoparticles: a study of formulation optimization, toxicity, and pharmacokinetics. Oncotarget. 8(7):12013-12030
Fu, A., Ma, S., Wei, N., Tan, B.X., Tan, E.Y., Luo, K.Q. (2016) High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin. Oncotarget. 7(31):50239-50257
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