ZFIN ID: ZDB-LAB-120411-1
Jian Zhang Laboratory
PI/Director: Zhang, Jian
Contact Person: Kuang, Xia
Email: kuangxia@genetics.ac.cn
Address: Institute of Genetics and Developmental Biology Chinese Academy of Sciences No.1 West Beichen Road Chaoyang District Beijing 100101 China
Country: China
Phone: 86-10-64852165
Fax: 86-10-64847018
Line Designation: gd

Show all 15 genomic features

We are interested in vertebrate early development, especially in maternal factors and germ layer specification.

Wang, Huawei Post-Doc Cheng, Feng Graduate Student Liu, Chao Graduate Student
Ma, Weirui Graduate Student Miao, Liyun Graduate Student Kuang, Xia Administrative Staff

Zhang, W., Guo, Y., Yang, J., Tang, G., Zhang, J., Cao, Y. (2023) Prodrug Based on Ionic Liquids for Dual-Triggered Release of Thiabendazole. ACS omega. 8:348434923484-3492
Wang, X., Ma, X., Wei, G., Ma, W., Zhang, Z., Chen, X., Gao, L., Liu, Z., Yuan, Y., Yi, L., Wang, J., Tokumoto, T., Huang, J., Chen, D., Zhang, J., Liu, J. (2021) The Role of DNA Methylation Reprogramming during Sex Determination and Transition in Zebrafish. Genomics, proteomics & bioinformatics. 19(1):48-63
Lin, Y., Chen, T., Mao, G., Qiu, T., Lan, Y., Xiang, X., Huang, J., Huang, J., Lu, T., Gan, S., Sun, X.D., Zhang, J. (2020) Long-term and in vivo assessment of Aβ protein induced brain atrophy in a zebrafish model by optical coherence tomography. Journal of biophotonics. 13(7):e202000067
Lin, Y., Xiang, X., Chen, T., Mao, G., Deng, L., Zeng, L., Zhang, J. (2019) In vivo monitoring the dynamic process of acute retinal hemorrhage and repair in zebrafish with spectral-domain optical coherence tomography. Journal of biophotonics. 12(12):e201900235
Chan, S.H., Tang, Y., Miao, L., Darwich-Codore, H., Vejnar, C.E., Beaudoin, J.D., Musaev, D., Fernandez, J.P., Benitez, M.D.J., Bazzini, A.A., Moreno-Mateos, M.A., Giraldez, A.J. (2019) Brd4 and P300 Confer Transcriptional Competency during Zygotic Genome Activation. Developmental Cell. 49:867-881.e8
Zhou, J., Zhao, H., Zhang, L., Liu, C., Feng, S., Ma, J., Li, Q., Ke, H., Wang, X., Liu, L., Liu, C., Su, X., Liu, Y., Yang, S. (2019) Integrated analysis of RNA-seq and microRNA-seq depicts miRNA-mRNA networks involved in stripe patterns of Botia superciliaris skin. Functional & integrative genomics. 19(5):827-838
Lin, Y., Xiang, X., Chen, T., Gao, C., Fu, H., Wang, L., Deng, L., Zeng, L., Zhang, J. (2019) In vivo monitoring and high-resolution characterizing of the prednisolone-induced osteoporotic process on adult zebrafish by optical coherence tomography. Biomedical Optics Express. 10:1184-1195
Zheng, Y., Liu, C., Li, Y., Jiang, H., Yang, P., Tang, J., Xu, Y., Wang, H., He, Y. (2018) Loss-of-function mutations with circadian rhythm regulator Per1/Per2 lead to premature ovarian insufficiency. Biology of reproduction. 100(4):1066-1072
Fernandez, J.P., Moreno-Mateos, M.A., Gohr, A., Miao, L., Chan, S.H., Irimia, M., Giraldez, A.J. (2018) RES complex is associated with intron definition and required for zebrafish early embryogenesis. PLoS Genetics. 14:e1007473
Chen, L., Wang, Y., Giesy, J.P., Chen, F., Shi, T., Chen, J., Xie, P. (2018) Microcystin-LR affects the hypothalamic-pituitary-inter-renal (HPI) axis in early life stages (embryos and larvae) of zebrafish. Environmental pollution (Barking, Essex : 1987). 241:540-548
Liu, C., Kim, Y.S., Kim, J., Pattison, J., Kamaid, A., Miller, Y.I. (2017) Modeling hypercholesterolemia and vascular lipid accumulation in LDL receptor mutant zebrafish. Journal of Lipid Research. 59(2):391-399
Zhang, J., Liu, J., Wang, L.M., Li, Z.Y., Yuan, Z. (2017) Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography. Journal of biophotonics. 10(6-7):878-886
Chen, D., Tang, J., Wan, Q., Zhang, J., Wang, K., Shen, Y., Yu, Y. (2017) E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway. Arteriosclerosis, Thrombosis, and Vascular Biology. 37(5):856-866
Liu, C., Gaudet, D., Miller, Y.I. (2017) Deficient Cholesterol Esterification in Plasma of apoc2 Knockout Zebrafish and Familial Chylomicronemia Patients. PLoS One. 12:e0169939
Miao, L., Yuan, Y., Cheng, F., Fang, J., Zhou, F., Ma, W., Jiang, Y., Huang, X., Wang, Y., Shan, L., Chen, D., Zhang, J. (2017) Translation repression by maternal RNA binding protein zar1 is essential for early oogenesis in zebrafish. Development (Cambridge, England). 144(1):128-138
Cheng, F., Miao, L., Wu, Q., Gong, X., Xiong, J., Zhang, J. (2016) Vinculin b deficiency causes epicardial hyperplasia and coronary vessel disorganization in zebrafish. Development (Cambridge, England). 143(19):3522-3531
Kuang, X., Liu, C., Fang, J., Ma, W., Zhang, J., Cui, S. (2016) The tumor suppressor gene lkb1 is essential for glucose homeostasis during zebrafish early development. FEBS letters. 590(14):2076-85
Gan, S., Huang, Z., Liu, N., Su, R., Xie, G., Zhong, B., Zhang, K., Wang, S., Hu, X., Zhang, J., Xiang, S. (2016) MicroRNA-140-5p impairs zebrafish embryonic bone development via targeting BMP-2. FEBS letters. 590(10):1438-46
Yuan, Y., Zhang, J., Zhou, Q. (2016) Overexpression of Jak1 Activating Mutants in Hepatocytes Is Insufficient to Generate Hepatocellular Carcinoma in Zebrafish. Journal of genetics and genomics = Yi chuan xue bao. 43:99-102
Wright, K.D., Mahoney Rogers, A.A., Zhang, J., Shim, K. (2015) Cooperative and independent functions of FGF and Wnt signaling during early inner ear development. BMC Developmental Biology. 15:33
Zhang, J., Ge, W., Yuan, Z. (2015) In vivo three-dimensional characterization of the adult zebrafish brain using a 1325 nm spectral-domain optical coherence tomography system with the 27 frame/s video rate. Biomedical Optics Express. 6:3932-40
Ma, W.R., Zhang, J. (2015) Jag1b is essential for patterning inner ear sensory cristae by regulating anterior morphogenetic tissue separation and preventing posterior cell death. Development (Cambridge, England). 142(4):763-73
Liu, C., Hu, J., Qu, C., Wang, L., Huang, G., Niu, P., Zhong, Z., Hong, F., Wang, G., Postlethwait, J.H., Wang, H. (2015) Molecular evolution and functional divergence of zebrafish (Danio rerio) cryptochrome genes. Scientific Reports. 5:8113
Gao, D., Xu, Z., Kuang, X., Qiao, P., Liu, S., Zhang, L., He, P., Jadwiga, W.S., Wang, Y., and Min, W. (2014) Molecular characterization and expression analysis of the autophagic gene Beclin 1 from the purse red common carp (Cyprinus carpio) exposed to cadmium. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 160:15-22
Fang, L., Liu, C., and Miller, Y.I. (2014) Zebrafish models of dyslipidemia: relevance to atherosclerosis and angiogenesis. Translational research : the journal of laboratory and clinical medicine. 163(2):99-108
Fang, L., Choi, S.H., Baek, J.S., Liu, C., Almazan, F., Ulrich, F., Wiesner, P., Taleb, A., Deer, E., Pattison, J., Torres-Vázquez, J., Li, A.C., and Miller, Y.I. (2013) Control of angiogenesis by AIBP-mediated cholesterol efflux. Nature. 498(7452):118-122
Liu, C., Ma, W., Su, W., and Zhang, J. (2012) Prdm14 acts upstream of islet2 transcription to regulate axon growth of primary motoneurons in zebrafish. Development (Cambridge, England). 139(24):4591-4600
Peng, J., Zhang, J., and Meng, A. (2012) The tiny zebrafish keep swimming fast in the developmental biology pond. Journal of genetics and genomics = Yi chuan xue bao. 39(9):419-420
Zhang, X., Zhao, H., Chen, Y., Liu, C., Meng, K., Yang, P., Wang, Y., Wang, G., and Yao, B. (2012) Characterization and biological function analysis of the trim3a gene from zebrafish (Danio rerio). Fish & shellfish immunology. 32(5):621-628