ZFIN Lab: Department of Physiology, Osaka Medical and Pharmaceutical University

ZFIN ID: ZDB-LAB-090710-2

Department of Physiology, Osaka Medical and Pharmaceutical University

PI/Director:	Ono, Fumihito
Contact Person:	Ono, Fumihito
Email:	fumihito.ono@ompu.ac.jp
URL:	https://www.ompu.ac.jp/department/physiology/Physiology-index.html
Address:	Department of Physiology, Osaka Medical and Pharmaceutical University 2-7 Diagaku-machi Takatsuki Osaka Japan 569-8686
Country:	Japan
Phone:	072-684-6421
Fax:	072-684-6521
Line Designation:	omc

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 10 genomic features

STATEMENT OF RESEARCH INTERESTS

Research key words: nervous system, synapse, muscle, ion channels, receptors

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Yamamoto, Y., Hishikawa, D., Ono, F. (2024) Trpv4-mediated apoptosis of Leydig cells induced by high temperature regulates sperm development and motility in zebrafish. Communications biology. 7:9696

Sakata, S., Ono, F. (2023) Allosteric inhibition of muscle-type nicotinic acetylcholine receptors by a neuromuscular blocking agent pancuronium. PLoS One. 18:e0292262e0292262

Yamashita, M., Egashira, Y., Nakamura, S., Sakata, S., Ono, F. (2022) Receptor subunit compositions underly distinct potencies of a muscle relaxant in fast and slow muscle fibers. Frontiers in Physiology. 13:1026646

Egashira, Y., Kumade, A., Ojida, A., Ono, F. (2022) Spontaneously recycling synaptic vesicles constitute readily releasable vesicles in intact neuromuscular synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 42(17):3523-3536

Zempo, B., Tanaka, N., Daikoku, E., Ono, F. (2021) High-speed camera recordings uncover previously unidentified elements of zebrafish mating behaviors integral to successful fertilization. Scientific Reports. 11:20228

Zempo, B., Yamamoto, Y., Williams, T., Ono, F. (2020) Synaptic silencing of fast muscle is compensated by rewired innervation of slow muscle. Science advances. 6:eaax8382

Fujii, K., Nakajo, K., Egashira, Y., Yamamoto, Y., Kitada, K., Taniguchi, K., Kawai, M., Tomiyama, H., Kawakami, K., Uchiyama, K., Ono, F. (2020) Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis. Cell Reports. 30:2879-2888.e3

Li, L., Jiao, X., D'Atri, I., Ono, F., Nelson, R., Chan, C.C., Nakaya, N., Ma, Z., Ma, Y., Cai, X., Zhang, L., Lin, S., Hameed, A., Chioza, B.A., Hardy, H., Arno, G., Hull, S., Khan, M.I., Fasham, J., Harlalka, G.V., Michaelides, M., Moore, A.T., Coban Akdemir, Z.H., Jhangiani, S., Lupski, J.R., Cremers, F.P.M., Qamar, R., Salman, A., Chilton, J., Self, J., Ayyagari, R., Kabir, F., Naeem, M.A., Ali, M., Akram, J., Sieving, P.A., Riazuddin, S., Baple, E.L., Riazuddin, S.A., Crosby, A.H., Hejtmancik, J.F. (2018) Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa. PLoS Genetics. 14:e1007504

Mott, M., Luna, V.M., Park, J.Y., Downes, G.B., Epley, K., Ono, F. (2017) Expressing acetylcholine receptors after innervation suppresses spontaneous vesicle release and causes muscle fatigue. Scientific Reports. 7:1674

Torvund, M.M., Ma, T.S., Connaughton, V.P., Ono, F., Nelson, R.F. (2017) Cone signals in monostratified and bistratified amacrine cells of adult zebrafish retina. The Journal of comparative neurology. 525(7):1532-1557

Luna, V.M., Daikoku, E., Ono, F. (2015) "Slow" skeletal muscles across vertebrate species. Cell & Bioscience. 5:62

Park, J.Y., Mott, M., Williams, T., Ikeda, H., Wen, H., Linhoff, M., Ono, F. (2014) A Single Mutation in the Acetylcholine Receptor δ-Subunit Causes Distinct Effects in Two Types of Neuromuscular Synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34:10211-10218

Puhl, H.L., Lu, V.B., Won, Y.J., Sasson, Y., Hirsch, J.A., Ono, F., Ikeda, S.R. (2014) Ancient Origins of RGK Protein Function: Modulation of Voltage-Gated Calcium Channels Preceded the Protostome and Deuterostome Split. PLoS One. 9:e100694

Fero, K., Bergeron, S.A., Horstick, E.J., Codore, H., Li, G.H., Ono, F., Dowling, J.J., and Burgess, H.A. (2014) Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure. Disease models & mechanisms. 7(2):289-98

Ikeda, H., Delargy, A.H., Yokogawa, T., Urban, J.M., Burgess, H.A., and Ono, F. (2013) Intrinsic properties of larval zebrafish neurons in ethanol. PLoS One. 8(5):e63318

Walogorsky, M., Mongeon, R., Wen, H., Nelson, N.R., Urban, J.M., Ono, F., Mandel, G., and Brehm, P. (2012) Zebrafish model for congenital myasthenic syndrome reveals mechanisms causal to developmental recovery. Proceedings of the National Academy of Sciences of the United States of America. 109(43):17711-17716

Papke, R.L., Ono, F., Stokes, C., Urban, J., and Boyd, R.T. (2012) The nicotinic acetylcholine receptors of zebrafish and an evaluation of pharmacological tools used for their study. Biochemical pharmacology. 84(3):352-365

Park, J.Y., Ikeda, H., Ikenaga, T., and Ono, F. (2012) Acetylcholine receptors enable the transport of rapsyn from the Golgi complex to the plasma membrane. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(21):7356-7363

Nakayama, S., Ikenaga, T., Kawakami, K., Ono, F., and Hatta, K. (2012) Transgenic line with gal4 insertion useful to study morphogenesis of craniofacial perichondrium, vascular endothelium-associated cells, floor plate, and dorsal midline radial glia during zebrafish development. Development, growth & differentiation. 54(2):202-215

Won, Y.J., Ono, F., and Ikeda, S.R. (2012) Characterization of na(+) and ca(2+) channels in zebrafish dorsal root ganglion neurons. PLoS One. 7(8):e42602

Mongeon, R., Walogorsky, M., Urban, J., Mandel, G., Ono, F., and Brehm, P. (2011) An acetylcholine receptor lacking both γ and ε subunits mediates transmission in zebrafish slow muscle synapses. The Journal of general physiology. 138(3):353-66

Ikenaga, T., Urban, J.M., Gebhart, N., Hatta, K., Kawakami, K., and Ono, F. (2011) Formation of the spinal network in zebrafish determined by domain-specific pax genes. The Journal of comparative neurology. 519(8):1562-1579

Diep, C.Q., Ma, D., Deo, R.C., Holm, T.M., Naylor, R.W., Arora, N., Wingert, R.A., Bollig, F., Djordjevic, G., Lichman, B., Zhu, H., Ikenaga, T., Ono, F., Englert, C., Cowan, C.A., Hukriede, N.A., Handin, R.I., and Davidson, A.J. (2011) Identification of adult nephron progenitors capable of kidney regeneration in zebrafish. Nature. 470(7332):95-100

Won, Y.J., Ono, F., and Ikeda, S.R. (2011) Identification and Modulation of Voltage-gated Ca2+ currents in Zebrafish Rohon-Beard Neurons. Journal of neurophysiology. 105(1):442-453

Epley, K.E., Urban, J.M., Ikenaga, T., and Ono, F. (2008) A modified acetylcholine receptor delta-subunit enables a null mutant to survive beyond sexual maturation. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(49):13223-13231

Luna, V.M., Wang, M., Ono, F., Gleason, M.R., Dallman, J.E., Mandel, G., and Brehm, P. (2004) Persistent electrical coupling and locomotory dysfunction in the zebrafish mutant shocked. Journal of neurophysiology. 92(4):2003-2009

Ibanez-Tallon, I., Wen, H., Miwa, J.M., Xing, J., Tekinay, A.B., Ono, F., Brehm, P., and Heintz, N. (2004) Tethering naturally occurring Peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo. Neuron. 43(3):305-311

Ono, F., Mandel, G., and Brehm, P. (2004) Acetylcholine receptors direct rapsyn clusters to the neuromuscular synapse in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(24):5475-5481