FIGURE 8
- ID
- ZDB-IMAGE-260720-15
- Publication
- Perone et al., 2026 - Aip mutation leads to significant alterations in gene expression, altered sensitivity to Ahr ligands, and early lethality in zebrafish
- All Figures
- Figures for Perone et al., 2026
|
FIGURE 8
The contribution of different cell types to the five dpf, bulk RNA-seq data as estimated by MuSiC for the aipwh86(A) and aipwh239(B) lines. Cell types are presented on the x-axis, and genotype/sample ID is on the y-axis. The color bar representing proportion is log-scaled to better display contrast in low proportion cell types. Cell types with significant differences in proportion between aip+/+ and aip−/− larvae are denoted with an asterisk, * (p-value ≤0.05, two-sided Wilcoxon rank sum test). Cell types trending towards significant differences were annotated with a period, (p-value ≤0.1, effect size greater than 0.7). Cell types that were significant or trending in both lines were denoted with a red asterisk or period. Differences in estimated cell-type contributions between genotypes may reflect transcriptomic changes within specific cell types associated with aip deficiency.