IMAGE

Fig. 3

ID: ZDB-IMAGE-260709-55
Publication: Valtorta et al., 2026 - Unprocessed U1 snRNAs as a biomarker of INTS11- and BRAT1-related neurodevelopmental disorders
All Figures: Figures for Valtorta et al., 2026

Image

Figure Caption

Fig. 3

Analysis of Integrator subunit protein levels in INTS11-mutated patient-derived cells. A Immunoblot analysis of INTS11, INTS9, and INTS4 protein levels in fibroblasts and lymphoblastoid cell lines (LCLs) derived from the healthy control, unaffected parents or INTS11-mutated patients. β-actin or α-tubulin was used as a loading control. A non-specific band is indicated by an asterisk (*). B Quantification of protein levels from (A), based on at least three independent experiments. Data are presented as mean ± SEM. Statistical significance was determined using a two-tailed Student’s t-test (ns – not significant, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001)

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genome Med.