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Biswas et al., 2026 - Canalization of neural dynamics by δ-protocadherins in the developing zebrafish optic tectum
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Fig. S5 Altered orientation selectivity in δ2-pcdh mutants.
A-D. Cumulative probability distributions of orientation selectivity for all neurons in (A) wild type (purple; n = 9),(B) pcdh19Δprom (teal; n = 9), (C) pcdh19-10bp (blue; n = 12) and (D) pcdh17-5bp (orange; n = 13) mutants. The distributions for individual fish are shown in thin lines and the distribution of the pooled data is shown as a thick line. As a reference, the pooled wild type data is shown in purple in each graph. Pcdh17 and Pcdh19 mutants exhibit distinct effects on orientation selectivity, with pcdh17-5bp mutants exhibiting an overall shift toward reduced orientation selectivity, and both pcdh19 mutants exhibiting a right shift toward increased orientation selectivity.(**p < 0.0001; Dunn’s test).

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