Fig. 6
- ID
- ZDB-IMAGE-260617-12
- Genes
- Antibodies
- Publication
- Martin et al., 2026 - Nr2f1a and Isl1 repress acquisition of epicardial identity in venous atrial cardiomyocytes
- All Figures
- Figures for Martin et al., 2026
|
Fig. 6 Co-expression of cardiomyocyte markers with tcf21:NLS-EGFP in nr2f1a;isl1 mutant hearts. (A-B‴) Optical sections of the venous pole of wild-type and nr2f1a−/−;isl1−/− hearts at 96 hpf stained for Myh6 (blue), myl7:DsRed2-NLS (red) and tcf21:NLS-EGFP (green). (A-A‴) Representative Myh6+/myl7:DsRed2-NSL+/tcf21:NLS-EGFP− cardiomyocytes in wild-type heart (white arrows). (B-B‴) Myh6+/myl7:DsRed2-NLS+/tcf21:NLS-EGFP+ cells in nr2f1a;isl1 mutant heart (yellow arrows). Wild type (n=8) and nr2f1a−/−;isl1−/− (n=5). Scale bar: 10 μm. (C) Quantification of Myh6+/myl7:DsRed2-NLS+/tcf21:NLS-EGFP+ cells in wild-type and nr2f1a−/−;isl1−/− hearts. P=0.0993 (two-tailed Welch's t-test). (D) Proportion of embryos with at least one Myh6+/myl7:DsRed2-NLS+/tcf21:NLS-EGFP+ cell in wild-type and nr2f1a−/−;isl1−/− hearts. (D) *P=0.0350 (Fisher's exact test).