Fig. 3

Fig. 3 Zebrafish gene organization of candidate genes share high homology with human orthologues. (A) Gene organization of human genes (yellow) and zebrafish gene (blue) orthologues share very similar exon numbers and coding exons. Exon maps were generated from the Ensembl database. Filled sections indicate coding exons; empty sections indicate non-coding exons. Chromosome number (ch), strand direction (FS, forward strand; RS, reverse strand) and gene size in kilobases (kb) are stated on exon maps. (B) Human and zebrafish protein sizes (aa, amino acids) of CTSZ and NCCRP1 encode proteins of very similar sizes. Zebrafish ocstamp is smaller than the human counterpart. Protein size was determined using the Ensembl database. (C) NCBI Blast Global Align comparing zebrafish sequences to human sequences identified high amino acid homology, depicted as percentage identities.