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Hernandez et al., 2026 - Insulin Induces Outer Blood-Retinal Barrier Disruption via Downregulation of Claudin-19
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Figure 1.

Claudin-19 is the claudin predominantly expressed in porcine RPE. (A) qPCR measuring claudin expression from cells collected at harvest and cells that were in culture for 2 weeks. Bars represent mean ± SD (n = 2). **P < 0.01; ****P < 0.0001 (one-way ANOVA with Brown–Forsythe test). (B) Western blot analysis of claudin-19 expression in primary porcine RPE cells that were in culture for 2 weeks (n = 2). (C) Immunofluorescent staining of claudin-19 (green) and ZO-1 (red) on porcine RPE tissue. Scale bar: 10 µm.

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