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FIGURE 2
Detection of OTC‐resistant bacteria‐associated 16S rRNA genes in the bacterial flora. (A) The proportion of 16S rRNA gene sequences associated with OTC‐resistant bacteria identified through culture experiments was analysed in the sequencing data of 16S rRNA gene amplicon library obtained from each sample. Data in same condition were merged and expressed by heat map. The bacteria increased abundance by OTC administration in four weeks were highlighted by dotted‐yellow squares. (B) Detection patterns of resistance‐associated taxa across samples. Red cells indicate proportions ≥ 0.05%, and blue cells indicate < 0.05%. Samples from Week 1 and Week 4 are shown together with the community classifications defined in (B).