Fig. 8

Fig. 8 Enriched Gene Ontology (GO) terms for differentially expressed genes (DEGs) between experimental groups. (A). GO enrichment analysis of DEGs of triploid (3n) zebrafish gonads compared to the diploid controls (2n) showing enrichment in GO terms related to regulation of mitosis, apoptosis and steroid metabolic processes. GO terms most relevant to our process of interest are indicated by red arrowheads. (B). GO enrichment analysis of DEGs for EE2 (17α-ethinylestradiol)-treated diploid compared to non-treated diploids (2n) zebrafish gonads, highlighting terms related to lipid and steroid metabolism, glucocorticoid metabolism and regulation of developmental process. GO terms most relevant to our process of interest are indicated by red arrowheads. The size of the black circles in the right side indicates the number of genes involved in each GO term, while the color bar represents the adjusted p-value (p.adjust), with red color indicating stronger statistical significance. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)