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Fig. 3 1,6-DHN induces cell proliferation and apoptosis in zebrafish.(A) Confocal projection images showing PCNA immunostaining in the liver of zebrafish larvae exposed to 5, 10, and 20 mg/L 1,6-DHN for 72 h.(B–E) mRNA levels of p53, bax, bcl2, and the bax/bcl2 ratio were measured by quantitative real-time PCR.Data are presented as mean ± SD from three independent experiments.(n = 20, *p < 0.05，**p < 0.01，***p < 0.001,mean ± S.D).Scale bar: 100 µm.
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