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Fig. 7 Inhibition effect of AAMA derivatives on B16F10 cellular melanin content. Derivatives 2 (A), 5 (B), and 6 (C) were used as test samples, and PTU and KA were used as positive reference substances. KA was tested at 20 μM, whereas 2, 5, 6, and PTU were tested at three different concentrations (3.2, 8, and 20 μM). Following 1 h of sample treatment, stimulators (IBMX/α-MSH [200 μM/1 μM]) were administered to B16F10 cells for 72 h. * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. group treated with stimulators; ### p < 0.001 vs. control.
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