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Figure 4.

ID: ZDB-IMAGE-251219-43
Publication: Stonkus et al., 2025 - A new role for PHYHD1 and related dioxygenases: demethylation of 2'-O-methylated nucleosides
All Figures: Figures for Stonkus et al., 2025

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Figure 4.

Molecular docking of 2′-O-methyladenosine (A, yellow) and 2′-O-methylcytidine (B, salmon pink) on the PHYHD1 crystal structure (PDB ID: 3OBZ) [31] using the Attracting Cavities 2.0 algorithm [55]. Docking results with the lowest ΔG_SP values (−7.0663 for 2′-O-methyladenosine and −6.9917 for 2′-O-methylcytidine) are shown. The active centre iron ion is depicted as orange, and 2-oxoglutarate is depicted as grey.

Acknowledgments

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