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FIGURE 1
Simplified schematic representation of the kynurenine pathway. Catabolism through the kynurenine pathway is the major route for tryptophan degradation which results in the production of a series of bioactive metabolites. The kynurenine metabolites themselves participate in many signaling pathways and their dysregulation has been shown to contribute to both cell homeostasis as well as disease etiology.
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Full text @ FASEB J.