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Figure 3.

ID: ZDB-IMAGE-251023-21
Publication: Jamialahmadi et al., 2025 - Genome-wide interaction study with BMI identifies CYP7A1 and GIPR as genetic modulators of MASLD
All Figures: Figures for Jamialahmadi et al., 2025

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Figure 3.

Forest plot for association of controlled attenuation parameter and magnetic resonance spectroscopy hepatic fat content with the UBXN2B/CYP7A1 rs7826120 T allele in four European replication cohorts. The association was examined by a linear regression analysis under an additive genetic model adjusted for age, sex, and BMI. Pooled effect estimates were calculated using inverse-variance–weighted fixed- and random-effects meta-analysis. I², τ² (between-study variance) and P-value for Cochran’s Q heterogeneity test have been reported to assess the betweenstudy heterogeneity. BMI, body mass index; CI, confidence interval; MAFALDA, Molecular Architecture of FAtty Liver Disease in patients with obesity undergoing bariatric surgery; NEO, the Netherlands Epidemiology of Obesity Study.

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