ZFIN Image: Peloggia et al., 2025, Fig. 6.

Image

Figure Caption

Fig. 6.

Notch signaling is required for paired ionocyte survival, but does not affect NCC-like ionocyte number. (A) Schematic of experimental design. (B) Number of NaR- and HR-like ionocyte pairs in DMSO controls and treated with the Notch inhibitor LY411575. Mann–Whitney test (P < 0.0001). (C) Number of NCC-like ionocytes in DMSO controls and treated with the Notch inhibitor LY411575. Mann-Whitney test (P = 0.811). (D–E’’) Representative maximum intensity projection confocal images of HCR RNA-FISH for trpv6 (yellow) and foxi3b (cyan) with DAPI stain (gray) in DMSO-treated (D–D’’) and LY411575-treated (E–E’’) olfactory pits. N = 14 olfactory pits per condition. Scale bars: 20 µm.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Chem. Senses