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Fig. 6 Morphological study of mice. (A–C) Morphology of mice control, HFD and HFD + RSE02, respectively. (D) Body weight of day 1, day 15 and day 30 of control, HFD and HFD + RSE02 mice, respectively. (E & F) Liver and brain weight of control, HFD and HFD + RSE02 mice, respectively. All data were taken from three random measurment. Mean values in each column do not differ significantly at p < 0.05. Comparison between control and treatment mean values was made by Dunnett’s multiple comparisons test. Where, “****” = p < 0.0001, “***” = p < 0.001, ““**” = p < 0.01, “*” = p < 0.1, “ns” = data is not significant. Data were subjected to analysis of variance (ANOVA ordinary one way) test.