Fig. 3

Fig. 3 Cmpk2 is primarily expressed in the neutrophils of ARDS A UMAP embedding of the single-cell RNA-sequencing profile from non-treated and treated ARDS patients (n = 8). Distinct clusters are annotated and color-coded. B The transcription levels of Cmpk2 in different cells. C Feature plot visualizing the expression of Cmpk2, the color of points (cells) represents the expression level of Cmpk2. D, F the clustering result of neutrophil D and macrophage F subpopulations from ARDS patients. Each point represents one single cell, colored according to cell type. E, G Feature plot displaying the expression of Cmpk2 in different subpopulations of neutrophils E and macrophages G, where the color gradient of the points (representing individual cells) corresponds to the expression level of Cmpk2