ZFIN Image: Clarke et al., 2025, Fig. 2

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Fig. 2

SBH attenuates markers of ferroptosis. HT22 hippocampal neurons were exposed to FAC (75 µM) for 24 h, in the presence and absence of SBH (10 µM) or ChB (50 µM). Cell viability was assessed by CCK-8 assay (A). Iron accumulation (B) and lipid peroxidation (C) were determined in HT22 cell protein lysates. The mRNA expression of Gpx4 (D), Hmox1 (E), and Acsl4 (F) was determined as key indicators of ferroptosis. Data is presented as mean ± SEM. ****p < 0.0001, two-way ANOVA and Bonferroni analysis. n = 9 replicates from 3 independent experiments

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Mol. Neurosci.