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Fig. 2 HL-60 cells are unaffected by CDs and empty liposomes but sustain a dose-dependent reduction in viability when treated with CPZ and CD/CPZ liposome formulations. HL-60 cells were measured for viability relative to control after incubation for 48 h with either: A) cyclodextrins (CD), B) empty dehydration-rehydration vesicles (DRV), or C) either free chlorpromazine (CPZ), CPZ-loaded DRV, or DRV loaded with CD/CPZ complexes. The results are shown as the mean ± SD of four wells measured by metabolic conversion of the MTS reagent.
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