IMAGE

Fig. 7

ID
ZDB-IMAGE-250602-27
Publication
Tian et al., 2025 - C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish (Danio rerio) body axis straightening
All Figures
Figures for Tian et al., 2025
Image
Figure Caption

Fig. 7 Model of SCO-spondin and RF in control and dpy19l1l-deficient zebrafish. (Top) In wild-type spinal cord, DPY19L1L C-mannosylates SCO-spondin (purple), enabling RF formation via cilia-driven CSF flow. (Bottom) In dpy19l1lāˆ’/āˆ’ mutants, nonglycosylated SCO-spondin (dark blue) fails to form RF, leading to body axis curvature. CSF-CN, CSF-contacting neuron.

Acknowledgments
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