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Fig. 15 PMF can modulate the expression of selected appetite responsible-orexigenic and -anorexigenic genes in zebrafish brain overfed for 6 weeks. Data represents as means (±SEM), n = 8. Statistical analyses were performed by Two-Way ANOVA followed by Bonferroni post-test and significant p-values indicated as ∗p<0.05, ∗∗p<0.01, ∗∗∗p<0.001 and ∗∗∗∗p<0.0001. mRNA expression values were normalized with β-Actin expressed as a ratio of the ND group. ND, normal diet; HFD, high fat diet.
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Reprinted from Molecular and Cellular Endocrinology, , Vohra, M.S., Ahmad, B., Taylor, E.R., Benchoula, K., Fong, I.L., Parhar, I.S., Ogawa, S., Serpell, C.J., Wong, E.H., 5,7,3',4',5'-Pentamethoxyflavone (PMF) Exhibits Anti-Obesity and Neuroprotective Effects in an Obese Zebrafish Model, 112554112554, Copyright (2025) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.