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Fig. 5 Curcumin improves defective tissue repair capacity in Cftr-depleted animals. (A-C) Control MO and cftr MO were treated with DMSO or curcumin prior to caudal fin amputation procedure, then injured and immediately put back in treatments for 4 h. The potential of tissue repair was evaluated at 72 hpA. (B) Brightfield microscopy of injured caudal fin showing tissue regeneration in cftr MO treated with curcumin versus DMSO (scale bars, 100 μm). (C) Measurement of regenerated caudal fin areas, lengths and widths following compounds exposure (n = 20, Two-way ANOVA, Tukey's multiple comparisons test).