Fig. 2 a) Synthesis of prodyes 1–5 a,b and Pt-mediated conversion into resorufin and EtNH-NBD. b, c) Comparative study of the conversion efficiencies (in %) after 24 h incubation. Reaction conditions: prodye (40 μM) and dPt-1–3 (40 μg/mL) in PBS at 37 °C. Error bars: ±SD (n=3). Significant differences relative to the highest conversion value are represented as * P≤0.05, ** P≤0.01, *** P≤0.001, **** P≤0.0001. d) Comparative study of the conversion efficiencies (in %) after 24 h incubation in PBS supplemented with serum (10 % FBS). Negative control (Ctl): prodye without nanocatalysts. Error bars: ±SD (n=3).
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Full text @ Angew. Chem. Int. Ed. Engl.