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Fig 4

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ZDB-IMAGE-250428-89
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Figures for Fernández et al., 2025
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Fig 4 Expression levels of il1b, il6, tnfa, cox1, cox2a and c-fos genes in zebrafish brain after pentylenetetrazol (PTZ)-induced seizures.

Each treatment group was pre-exposed to CX2 for 24 h, followed by exposure to 15 mM PTZ for 20 min. Control and PTZ groups underwent identical procedures but were exposed to water only (n = 5 per group). Data are presented as mean ± SEM. Statistical analyses were performed with the one-way ANOVA, followed by Bonferroni’s multiple comparisons test. Differences were significant at p<0.05. Significance indicators: *p≤0.05; **p≤0.01; ***p≤0.001; ****p≤0.0001. Groups: Control (Control), PTZ (pentylenetetrazol group), T0.5 (0.5 µM treatment), T0.1 (0.1 µM treatment), T0.05 (0.05 µM treatment).

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