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Fig. 9 SRF interacts with CRIP2, and the expression of its downstream genes is modulated by CRIP2. (A) Immunofluorescence analysis of PDE10A expression after CRIP2 depletion. DAPI was used to stain the nucleus. (B) Detection of SRF in the immunoprecipitation derived from cell lines overexpressing CRIP2. (C) CRIP2 coimmunoprecipitates with SRF. (D–I) Analysis of the altered protein levels of PDE10A, SRF, PDGFB, IL-11R, p21, and CDK2 in response to CRIP2 deficiency
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