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FIGURE 7

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Publication: Strachan et al., 2025 - Novel in vivo models of autosomal optic atrophy reveal conserved pathological changes in neuronal mitochondrial structure and function
All Figures: Figures for Strachan et al., 2025

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FIGURE 7

Altered mitochondrial morphology within motor neuron axons in Opa1 neuronal KO Drosophila. (A) Representative confocal images of mitochondria (green) within motor neuron axons. Larvae are progeny of UAS‐Cas9;d42GAL4.UAS‐mitoGFP flies crossed to w¹¹¹⁸ (control) or Opa1 sgRNA (Opa1 neuronal KO) flies. Graphs represent mean ± SD mitochondrial size (B) and circularity (C). Statistics consist of two‐tailed t‐tests.

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