IMAGE

FIGURE 5

ID
ZDB-IMAGE-250411-6
Publication
Strachan et al., 2025 - Novel in vivo models of autosomal optic atrophy reveal conserved pathological changes in neuronal mitochondrial structure and function
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Figures for Strachan et al., 2025
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Figure Caption

FIGURE 5

Most significantly altered proteins identified by proteomic profiling in Opa1 loss of function models. (A) Tables show the 10 most up‐ (upper panel) and down‐ (lower panel) regulated proteins in opa1 crispants compared to buffer‐injected controls. (B) Tables show the 10 most up‐ (upper panel) and down‐ (lower panel) regulated proteins in progeny of elav‐GAL4.UAS‐Cas9 crossed to either w1118 (control) or Opa1 sgRNA (Opa1 neuronal KO) flies.

Acknowledgments
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