Figure 5

Figure 5

Effect of banaba leaf extract and policosanol (alone or in combination) on the lipoprotein profile and oxidative and antioxidant variables of plasma from the hyperlipidemic zebrafish treated with streptozotocin (n = 12). (A) Total cholesterol (TC), (B) triglycerides (TGs), (C) high-density lipoprotein cholesterol (HDL-C), (D) low-density lipoprotein cholesterol (LDL-C), (E) malondialdehyde (MDA), (F) sulfhydryl content, (G) paraoxonase (PON), and (H) ferric ion reduction (FRA) ability. Each analysis was performed using triplicate experiments with duplicate samples, resulting in a total of six replicates (n = 6). Abbreviations: HCD (high cholesterol diet), STZ (streptozotocin), BNB (banaba), and PCO (policosanol). The symbols *, **, and *** underline the statistical significance at p < 0.05, p < 0.01, and p < 0.001, respectively, vs. the HCD+STZ group. †, ††, and ††† indicate statistical significance at p < 0.05, p < 0.01, and 0.001 vs. the BNB+PCO group; ns represents a non-significant (p > 0.05) difference vs. the HCD+STZ group.