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Publication: Le et al., 2025 - A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression
All Figures: Figures for Le et al., 2025

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FIGURE 3

Representative images of zebrafish eyes stained with H&E from control and crim1^−/− larvae that are homozygous for a 2 base pair deletion, c.339_340delCT p.Leu112Leufs*3, at 3–5 days post fertilization (dpf). The top row shows control larvae at 3 dpf (A), 4 dpf (B, C), and 5 dpf (D), showing normal lens and eye development. The bottom row shows homozygous crim1^−/− larvae at 3 dpf (E), 4 dpf (F, G), and 5 dpf (H), showing reduced lens and eye size in the crim1^−/− lenses at 3 and 4 dpf (E, F). At 3 dpf, 6–8 larvae were scored, and at 4 and 5 dpf, 10–12 larvae were scored. Scale bar = 50 µm.

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