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Fig. 5 Fluticasone propionate promotes fkbp5 expression and inhibits cyp3a65 expression in both GFP intensity (as clobetasol propionate) and mRNA expression. mRNA expression of (A) fkbp5 and (B) cyp3a65 in pooled zebrafish embryos (n = 5 embryos/pool) when exposed to FLU 0.23 µM. GFP intensity in individuals (n = 21 embryos minimum per condition) after exposure to (C) FLU and (D) CLOBE. In (D) FLU is for comparison and TCDD as positive control. Control condition (CTRL) is DMSO 0.01%.
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Full text @ Aquat. Toxicol.