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Fig. 7 Baicalein inhibits the effect of ISO on apoptosis and oxidative stress in vivo. (a–b) The quantification of TUNEL-positive cell number per high-power field (scale bars, 50 μm; n ≥ 3 in each group). #p < 0.05, versus CON, *p < 0.05, **p < 0.01 versus ISO. n ≥ 3. The protein levels of Caspase3 (c, d), Caspase9 (c, e), Cleaved-PARP (c, f) in cardiac of mice were determined by Western-blot. Outcomes are displayed as average ±SD (n ≥ 3). ##p < 0.01, versus CON, *p < 0.05, **p < 0.01, ***p < 0.001 versus ISO. n ≥ 3. The expression of MDA (g), GSH (h) and SOD (i) during oxidative stress in the mouse serum was determined by ELISA (n ≥ 3). #p < 0.05, ##p < 0.01, ###p < 0.001, versus CON, *p < 0.05, **p < 0.01, versus ISO.