ZFIN Image: Xia et al., 2025, Figure 5

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Figure 5

Phenotypic comparison between ctdsp2^−/− mutants and wildtype zebrafish embryos from 1 to 5 days post-fertilization (dpf): (A–D) No significant phenotypic differences were observed between the two groups at 1 dpf and 2 dpf. (E–J) ctdsp2^−/− embryos abnormally lacked visible signs of mandible development and exhibited cranial developmental abnormalities and microphthalmia compared to wildtypes from 3 dpf. The differences persisted until 5 dpf (I,J), with all ctdsp2^−/− embryos dying of swallowing difficulties and cardiac edema.

Acknowledgments

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