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Fig. 1 Structural characteristics of Igldcp and orthology analysis. A) Domain composition of Igldcp proteins from different fish species determined with SMART software. B) Schematic representation of the spatial organization of zebrafish Igldcp. C) Predicted 3D structure of zebrafish Igldcp using the I-TASSER server. The model with the best C-score was selected. D) Fish-enriched chordate orthology analysis of Igldcp constructed with OrthoFinder. The igldcp genes, represented in purple, were found to be absent outside the subclass Neopterygii. Salmonids and cyprinids contained two copies of the igldcp gene, except for zebrafish, which contained only one copy. The presence of two copies in salmonids and cyprinid species may be due to the additional genome duplication events in these fish families. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)