ZFIN Image: Zheng et al., 2025, Figure 5

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Figure 5

Molecular diversity of embryonic zebrafish after OTA treatment. (A) PCA analysis of RNA-seq results showing the heterogeneity of control and OTA-treated zebrafish embryos. (B) Volcano plot showing differential expressed genes between control and OTA-treated embryos. (C, D) Representative GO and KEGG terms of upregulated (C) and downregulated (D) genes following OTA treatment. (E, F) Sankey diagram of specific genes involved in the GO and KEGG terms showed in (C, D). (G) GSEA analysis showing apoptosis, necroptosis, and PPAR signaling pathway related genes in control and OTA-treated embryos.

Acknowledgments

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